Axenic growth up-regulates mass-specific metabolic rate, stress resistance, and extends life span in Caenorhabditis elegans
K Houthoofd, BP Braeckman, I Lenaerts, K Brys… - Experimental …, 2002 - Elsevier
Culture in axenic medium causes two-fold increases in the length of development and adult
life span in Caenorhabditis elegans. We asked whether axenic medium imposes dietary …
life span in Caenorhabditis elegans. We asked whether axenic medium imposes dietary …
Life extension via dietary restriction is independent of the Ins/IGF-1 signalling pathway in Caenorhabditis elegans
K Houthoofd, BP Braeckman, TE Johnson… - Experimental …, 2003 - Elsevier
Dietary restriction (DR) increases life span in a wide variety of animals. In Caenorhabditis
elegans both reduced bacterial concentration (BDR) and culture on non-bacterial, semi …
elegans both reduced bacterial concentration (BDR) and culture on non-bacterial, semi …
Developmental biomarkers of aging in Caenorhabditis elegans
The developmental process of the nematode Caenorhabditis elegans is famously invariant;
however, these animals have surprisingly variable lifespans, even in extremely …
however, these animals have surprisingly variable lifespans, even in extremely …
A method for the isolation of longevity mutants in the nematode Caenorhabditis elegans and initial results
MR Klass - Mechanisms of ageing and development, 1983 - Elsevier
The free-living nematode Caenorhabditis elegans is used as a genetically manipulable
experimental system for the study of aging. Utilizing a temperature-sensitive sterile strain …
experimental system for the study of aging. Utilizing a temperature-sensitive sterile strain …
The nematode Caenorhabditis elegans as a model for aging research
HID Mack, T Heimbucher, CT Murphy - Drug Discovery Today: Disease …, 2018 - Elsevier
The nematode Caenorhabditis elegans is a key model system for experimental research on
the genetic regulation of aging, and has paved the way towards many important discoveries …
the genetic regulation of aging, and has paved the way towards many important discoveries …
Delayed development and lifespan extension as features of metabolic lifestyle alteration in C. elegans under dietary restriction
NJ Szewczyk, IA Udranszky, E Kozak… - Journal of …, 2006 - journals.biologists.com
Studies of the model organism Caenorhabditis elegans have almost exclusively utilized
growth on a bacterial diet. Such culturing presents a challenge to automation of …
growth on a bacterial diet. Such culturing presents a challenge to automation of …
The dietary restriction effect in C. elegans and humans: is the worm a one-millimeter human?
BP Braeckman, L Demetrius, JR Vanfleteren - Biogerontology, 2006 - Springer
Dietary restriction (DR) lengthens life span in wide range of vertebrate and invertebrate
species. The molecular mechanism by which DR increases life span and the universality of …
species. The molecular mechanism by which DR increases life span and the universality of …
Aging in the nematode Caenorhabditis elegans: major biological and environmental factors influencing life span
MR Klass - Mechanisms of ageing and development, 1977 - Elsevier
The free-living nematode Caenorhabditis elegans is an excellent experimental system for
the study of aging. The present study identifies some of the major biological and …
the study of aging. The present study identifies some of the major biological and …
The effects of Bacillus subtilis on Caenorhabditis elegans fitness after heat stress
Microbes can provide their hosts with protection from biotic and abiotic factors. While many
studies have examined how certain bacteria can increase host lifespan, fewer studies have …
studies have examined how certain bacteria can increase host lifespan, fewer studies have …
Using C. elegans for aging research
HA Tissenbaum - Invertebrate reproduction & development, 2015 - Taylor & Francis
Over a century ago, the zoologist Emile Maupas first identified the nematode, Rhabditis
elegans, in the soil in Algiers. Subsequent work and phylogenic studies renamed the …
elegans, in the soil in Algiers. Subsequent work and phylogenic studies renamed the …