Thermal variation reveals natural variation between isolates of Caenorhabditis elegans

SC Harvey, ME Viney - Journal of Experimental Zoology Part B …, 2007 - Wiley Online Library
The free‐living nematode Caenorhabditis elegans is distributed globally and found in many
varied habitats. However, in comparison to our understanding of the genetics of the species …

Natural Variation for Lifespan and Stress Response in the Nematode Caenorhabditis remanei

RM Reynolds, PC Phillips - PLoS One, 2013 - journals.plos.org
Genetic approaches (eg mutation, RNA interference) in model organisms, particularly the
nematode Caenorhabditis elegans, have yielded a wealth of information on cellular …

Long-lived worms and aging

Y Luo - Redox report, 2004 - Taylor & Francis
Several investigators have generated long-lived nematode worms (Caenorhabditis elegans)
in the past decade by mutation of genes in the organism in order to study the genetics of …

Genetic and pharmacological factors that influence reproductive aging in nematodes

SE Hughes, K Evason, C Xiong, K Kornfeld - PLoS genetics, 2007 - journals.plos.org
Age-related degenerative changes in the reproductive system are an important aspect of
aging, because reproductive success is the major determinant of evolutionary fitness …

[HTML][HTML] Explaining inter-lab variance in C. elegans N2 lifespan: Making a case for standardized reporting to enhance reproducibility

ND Urban, JP Cavataio, Y Berry, B Vang… - Experimental …, 2021 - Elsevier
The nematode Caenorhabditis elegans is a powerful model organism for studying cell
development, apoptosis, neuronal circuits, and aging. The isolate N2 is recognized by the C …

[引用][C] Analysis of the biological basis of aging in the nematode, with special emphasis on Caenorhabditis elegans

TE Johnson - Invertebrate models in aging research, 1984 - CRC Press Boca Raton, FL

WormFarm: a quantitative control and measurement device toward automated Caenorhabditis elegans aging analysis

B Xian, J Shen, W Chen, N Sun, N Qiao, D Jiang… - Aging cell, 2013 - Wiley Online Library
C aenorhabditis elegans is a leading model organism for studying the basic mechanisms of
aging. Progress has been limited, however, by the lack of an automated system for …

[引用][C] Genes That Determine Both Thermotolerance and Rate of Aging in Caenorhabditis elegansa

GA Walker, DW Walker… - Annals of the New York …, 1998 - Wiley Online Library
Caenorhabditis elegans is an excellent experimental system for the genetic dissection of
complex processes such as development, cell death, and aging. 1 This organism may now …

Evolution of male longevity bias in nematodes

D McCulloch, D Gems - Aging Cell, 2003 - Wiley Online Library
Many animal species exhibit sex differences in aging. In the nematode Caenorhabditis
elegans, under conditions that minimize mortality, males are the longer‐lived sex. In a …

[HTML][HTML] Effect of dietary restriction on health span in Caenorhabditis elegans: A systematic review

J Loo, MAFS Bana, JK Tan, JA Goon - Experimental Gerontology, 2023 - Elsevier
Dietary restriction (DR) interventions have demonstrated their efficacy in extending lifespan;
however, the association between lifespan extension and health span remains unclear. This …