Further evidence for a maternal genetic effect and a sex‐influenced effect contributing to risk for human neural tube defects

KL Deak, DG Siegel, TM George… - … Research Part A …, 2008 - Wiley Online Library
BACKGROUND: Neural tube defects (NTDs), including spina bifida and anencephaly, are
the second most common birth defect with an incidence of 1/1000. Genetic factors are …

Epidemiology of neural tube defects

LE Mitchell - American journal of medical genetics Part C …, 2005 - Wiley Online Library
The epidemiological investigation of the common open neural tube defects (NTDs),
anencephaly, and spina bifida, has a long history. The most significant finding from these …

Proportion of neural tube defects attributable to known risk factors

AJ Agopian, SC Tinker, PJ Lupo, MA Canfield… - 2013 - Wiley Online Library
BACKGROUND Recognized risk factors for neural tube defects (NTDs) poorly predict
population‐level NTD risk. However, the proportion of NTDs that can be attributed to these …

Etiologic heterogeneity of neural tube defects. II. Clues from family studies.

MJ Khoury, JD Erickson, LM James - American Journal of Human …, 1982 - ncbi.nlm.nih.gov
We previously reported that among neural tube defects (NTDs) with no known causes the
ones that occur alone (singles) have different epidemiologic characteristics from those that …

Epidemiologic and genetic aspects of spina bifida and other neural tube defects

KS Au, A Ashley‐Koch… - Developmental disabilities …, 2010 - Wiley Online Library
The worldwide incidence of neural tube defects (NTDs) ranges from 1.0 to 10.0 per 1,000
births with almost equal frequencies between two major categories: anencephaly and spina …

Genetic susceptibility to neural tube defect pregnancy varies with offspring phenotype

CL Relton, CS Wilding, PA Jonas, SA Lynch… - Clinical …, 2003 - Wiley Online Library
Neural tube defects (NTDs) have a well‐established genetic basis, although no single
genetic factor has been identified as a major risk factor in NTD susceptibility. A large number …

Epidemiologic characteristics of phenotypically distinct neural tube defects among 0.7 million California births, 1983–1987

GM Shaw, NG Jensvold, CR Wasserman… - Teratology, 1994 - Wiley Online Library
Isolated neural tube defects (NTDs) appear to have different risk factors compared to
nonisolated NTDs. To extend those observations, we explored routinely collected child and …

Maternal, paternal, and neonatal risk factors for neural tube defects: a systematic review and meta-analysis

S Jia, X Wei, L Ma, Y Wang, H Gu, D Liu, W Ma… - International Journal of …, 2019 - Elsevier
Abstract Objective Neural tube defects [NTDs] are severe congenital anomalies. The
etiology of NTDs is not fully known, and studies on the potential risk factors of NTDs present …

[HTML][HTML] Edad materna y defectos del tubo neural: evidencia para un efecto mayor en espina bífida que anencefalia

AR Vieira, S Castillo Taucher - Revista medica de Chile, 2005 - SciELO Chile
Resumen VIEIRA, Alexandre R. y CASTILLO TAUCHER, Silvia. Influence of maternal age
on the risk for neural tube defects, a meta analysis. Rev. méd. Chile [online]. 2005, vol. 133 …

Neural tube defects among twin births.

GC Windham, LE Sever - American Journal of Human Genetics, 1982 - ncbi.nlm.nih.gov
To obtain accurate, unbiased rates of neural tube defects (NTDs) in twins, we conducted a
population-based study that included live births and fetal deaths in Los Angeles County …