Dietary restriction improves fitness of aging parents but reduces fitness of their offspring in nematodes

BS Mautz, MI Lind, AA Maklakov - The Journals of Gerontology …, 2020 - academic.oup.com
Dietary restriction (DR) is a well-established intervention to extend lifespan across taxa.
Recent studies suggest that DR-driven lifespan extension can be cost-free, calling into …

Transgenerational fitness effects of lifespan extension by dietary restriction in Caenorhabditis elegans

ER Ivimey-Cook, K Sales… - … of the Royal …, 2021 - royalsocietypublishing.org
Dietary restriction (DR) increases lifespan in a broad variety of organisms and improves
health in humans. However, long-term transgenerational consequences of dietary …

Aging parasites produce offspring with poor fitness prospects

C Lippens, B Faivre, C Lechenault… - Biology …, 2017 - royalsocietypublishing.org
Senescing individuals have poor survival prospects and low fecundity. They can also
produce offspring with reduced survival and reproductive success. We tested the effect of …

Evolution of male longevity bias in nematodes

D McCulloch, D Gems - Aging Cell, 2003 - Wiley Online Library
Many animal species exhibit sex differences in aging. In the nematode Caenorhabditis
elegans, under conditions that minimize mortality, males are the longer‐lived sex. In a …

Dietary restriction by bacterial deprivation increases life span in wild-derived nematodes

GL Sutphin, M Kaeberlein - Experimental gerontology, 2008 - Elsevier
Dietary restriction is known to promote longevity in a variety of eukaryotic organisms. Most
studies of dietary restriction have been performed on animals bred for many generations …

The effect of dietary restriction on reproduction: a meta-analytic perspective

JP Moatt, S Nakagawa, M Lagisz, CA Walling - BMC Evolutionary Biology, 2016 - Springer
Background Dietary restriction (DR), a reduction in the amount of food or particular nutrients
eaten, is the most consistent environmental manipulation to extend lifespan and protect …

Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans

ED Smith, TL Kaeberlein, BT Lydum, J Sager… - BMC developmental …, 2008 - Springer
Background Dietary restriction (DR) increases life span and delays age-associated disease
in many organisms. The mechanism by which DR enhances longevity is not well …

Comparative and meta‐analytic insights into life extension via dietary restriction

S Nakagawa, M Lagisz, KL Hector, HG Spencer - Aging cell, 2012 - Wiley Online Library
Dietary restriction (DR) extends the lifespan of a wide range of species, although the
universality of this effect has never been quantitatively examined. Here, we report the first …

Ageing as “early-life inertia”: Disentangling life-history trade-offs along a lifetime of an individual

H Carlsson, E Ivimey-Cook, EML Duxbury… - Evolution …, 2021 - academic.oup.com
The theory that ageing evolves because of competitive resource allocation between the
soma and the germline has been challenged by studies showing that somatic maintenance …

Genetic and pharmacological factors that influence reproductive aging in nematodes

SE Hughes, K Evason, C Xiong, K Kornfeld - PLoS genetics, 2007 - journals.plos.org
Age-related degenerative changes in the reproductive system are an important aspect of
aging, because reproductive success is the major determinant of evolutionary fitness …