The epidemiological investigation of the common open neural tube defects (NTDs),
anencephaly, and spina bifida, has a long history. The most significant finding from these …

BACKGROUND: Neural tube defects (NTDs), including spina bifida and anencephaly, are
the second most common birth defect with an incidence of 1/1000. Genetic factors are …

Neural tube defects (NTDs) are multifactorial in their etiology, having both genetic and
environmental factors contributing to their development. Recent evidence demonstrates that …

Neural tube defects (NTDs) are common, serious malformations with a complex etiology that
suggests involvement of both genetic and environmental factors. The authors evaluated …

In this paper, we trace the history of current research into the genetic and biochemical
mechanisms that underlie folate‐preventable neural tube defects (NTDs). The inspired …

We previously reported that among neural tube defects (NTDs) with no known causes the
ones that occur alone (singles) have different epidemiologic characteristics from those that …

Neural tube defects (NTDs) are common congenital malformations in humans. While
etiologically heterogeneous, for the most part they are multifactorial in their pathogenesis …

BACKGROUND Recognized risk factors for neural tube defects (NTDs) poorly predict
population‐level NTD risk. However, the proportion of NTDs that can be attributed to these …

Several studies have reported that neural tube defects (NTD) occur more frequently among
children born to women of lower socio‐economic status (SES). This study investigated the …

The worldwide incidence of neural tube defects (NTDs) ranges from 1.0 to 10.0 per 1,000
births with almost equal frequencies between two major categories: anencephaly and spina …