Neural tube defects (NTDs) are serious malformations affecting approximately 1 per 1000
births, yet the mechanisms by which they arise are unknown. There have been consistent …

Neural tube defects (NTDs) represent a common group of severe congenital malformations
of the central nervous system. They result from failure of neural tube closure during early …

Objectives. To conduct surveillance for neural tube defects (NTDs) in a high-risk region of
the United States and to prevent occurrence and recurrence of NTDs through the …

Spina bifida and anencephaly, the common form of neural tube defects, affect approximately
300 000 newborns each year worldwide. The effectiveness of folic acid supplementation in …

OBJECTIVE: To prevent the recurrence of neural tube defects (NTDs) in families at
increased risk of having offspring with NTDs with the use of periconceptional folic acid …

Neural tube defects (NTDs) are common complex congenital malformations resulting from
failure of the neural tube closure during embryogenesis. It is established that folic acid …

Neural tube defects (NTDs), including spina bifida and anencephaly, are severe birth
defects of the central nervous system that originate during embryonic development when the …

Spina bifida, anencephaly, and encephalocele are commonly grouped together and termed
neural tube defects (NTD). Failure of closure of the neural tube during development results …

A protective effect of folate against the development of neural tube defects (NTDs),
specifically, anencephaly and spina bifida, is now well recognized, having been established …

Birth defects (congenital anomalies) are the leading cause of death in babies under 1 year
of age. Neural tube defects (NTD), with a birth incidence of approximately 1/1000 in …