Maternal vitamin levels during pregnancies producing infants with neural tube defects
JL Mills, J Tuomilehto, FY Kai, N Colman… - The Journal of …, 1992 - Elsevier
Women at very high risk for having a child with a neural tube defect (NTD) because they had
previously delivered affected children significantly reduced their recurrence rate by taking …
previously delivered affected children significantly reduced their recurrence rate by taking …
Reduction of birth prevalence rates of neural tube defects after folic acid fortification in Chile
JS López‐Camelo, IM Orioli, MG Dutra… - American Journal of …, 2005 - Wiley Online Library
To verify whether the decreasing neural tube defects birth prevalence rates in Chile are due
to folic acid fortification or to pre‐existing decreasing trends, we performed a population …
to folic acid fortification or to pre‐existing decreasing trends, we performed a population …
Folic acid for the prevention of neural tube defects
American Academy of Pediatrics Committee on … - Pediatrics, 1999 - cir.nii.ac.jp
抄録< jats: p> The American Academy of Pediatrics endorses the US Public Health Service
(USPHS) recommendation that all women capable of becoming pregnant consume 400 μg …
(USPHS) recommendation that all women capable of becoming pregnant consume 400 μg …
Nutritional and genetic determinants of vitamin B and homocysteine metabolisms in neural tube defects: a multicenter case–control study
M Candito, R Rivet, B Herbeth… - American Journal of …, 2008 - Wiley Online Library
Neural tube defects (NTDs) are severe congenital malformations due to failure of neural
tube formation in early pregnancy. The proof that folic acid prevents NTDs raises the …
tube formation in early pregnancy. The proof that folic acid prevents NTDs raises the …
Prevention of neural tube defects in the UK: a missed opportunity
Objective In 1991, the Medical Research Council (MRC) Vitamin Study demonstrated that
folic acid taken before pregnancy and in early pregnancy reduced the risk of a neural tube …
folic acid taken before pregnancy and in early pregnancy reduced the risk of a neural tube …
Is excess folic acid supplementation a risk factor for autism?
CM Beard, LA Panser, SK Katusic - Medical hypotheses, 2011 - Elsevier
BACKGROUND: The objective was to assess the association between increasing autism
incidence rates and the increasing dose of folic acid in prescription prenatal and pediatric …
incidence rates and the increasing dose of folic acid in prescription prenatal and pediatric …
Genetic polymorphisms in methylenetetrahydrofolate reductase and methionine synthase, folate levels in red blood cells, and risk of neural tube defects
Folic acid administration to women in the periconceptional period reduces the occurrence of
neural tube defects (NTDs) in their offspring. A polymorphism in the gene encoding …
neural tube defects (NTDs) in their offspring. A polymorphism in the gene encoding …
Not all cases of neural-tube defect can be prevented by increasing the intake of folic acid
Some countries have introduced mandatory folic acid fortification, whereas others support
periconceptional supplementation of women in childbearing age. Several European …
periconceptional supplementation of women in childbearing age. Several European …
Gene–gene interaction in folate-related genes and risk of neural tube defects in a UK population
Objective: To investigate the contribution of polymorphic variation in genes involved in the
folate-dependent homocysteine pathway in the aetiology of neural tube defects (NTD) …
folate-dependent homocysteine pathway in the aetiology of neural tube defects (NTD) …
Impact of folic acid fortification of the US food supply on the occurrence of neural tube defects
MA Honein, LJ Paulozzi, TJ Mathews, JD Erickson… - Jama, 2001 - jamanetwork.com
ContextDaily consumption of 400 µg of folic acid before conception and during early
pregnancy dramatically reduces the occurrence of neural tube defects (NTDs). Before food …
pregnancy dramatically reduces the occurrence of neural tube defects (NTDs). Before food …