Current initiatives such as the National Institute of Mental Health's Research Domain Criteria
project aim to reorganize classification of mental disorders along neurobiological lines …

Two approaches to the neurobiological study of mental disorders have predominated for
many years up to the present. One is the psychometric–dimensional approach, which relies …

Research into the neurobiological substrates of psychopathology has been impeded by
heterogeneity within diagnostic categories, comorbidity among mental disorders, and the …

Although personality traits have been linked to internalizing and externalizing
psychopathology, the extent to which these traits and psychopathological phenotypes share …

This review discusses issues and controversies with respect to the construct of a mental
disorder, models of etiology and pathology, and domains of psychopathology. Fundamental …

Abstract Background The National Institute of Mental Health Research Domain Criteria
initiative encourages a search for dimensional biological measures of psychopathology …

Dimensional approaches to psychiatric nosology are rapidly transforming the way
researchers and clinicians conceptualize personality pathology, leading to a growing …

Research on the nature and development of personality disorders has grown immensely
over the past thirty years. A selective summary overview is given of the current status of the …

The translation from psychiatric core symptoms to brain functions and vice versa is a largely
unresolved issue. In particular, the search for disorders of single brain regions explaining …

Psychopathology researchers have come to recognize that the boundaries between
putatively distinct psychiatric disorders do not cleanly map to the more complex …