[HTML][HTML] Clinical relevancy of circulating tumor cells in breast cancer: epithelial or mesenchymal characteristics, single cells or clusters?

I Fridrichova, L Kalinkova, S Ciernikova - International Journal of …, 2022 - mdpi.com
Metastatic breast cancer (MBC) is typically an incurable disease with high mortality rates;
thus, early identification of metastatic features and disease recurrence through precise …

Epigenetics of circulating tumor cells in breast cancer

A Bao-Caamano, A Rodriguez-Casanova… - Circulating Tumor Cells …, 2020 - Springer
Liquid biopsy based on the analysis of circulating tumor cells (CTCs) has emerged as an
important field of research. Molecular characterization of CTCs can provide insights into …

The prognostic impact of circulating tumor cells in subtypes of metastatic breast cancer

M Wallwiener, AD Hartkopf, I Baccelli… - Breast cancer research …, 2013 - Springer
The detection of circulating tumor cells (CTCs) in the peripheral blood of metastatic breast
cancer (MBC) patients is an independent marker of prognosis. This large prospective …

[HTML][HTML] Dynamics of circulating tumor cells in early breast cancer under neoadjuvant therapy

M José Serrano, P Sanchez Rovira… - Experimental and …, 2012 - spandidos-publications.com
At present, the majority of patients with breast cancer are diagnosed at early stages of
disease development. However, a considerable number of such cases develop secondary …

Towards an optimized platform for the detection, enrichment, and semi-quantitation circulating tumor cells

TJ Molloy, AJ Bosma, LJ van't Veer - Breast cancer research and treatment, 2008 - Springer
Metastasis describes the process of migration of a frequently clinically occult circulating
tumor cell (CTC) from the primary lesion to a new location and the subsequent formation of …

Genomic profiling of isolated circulating tumor cells from metastatic breast cancer patients

MJM Magbanua, EV Sosa, R Roy, LE Eisenbud… - Cancer research, 2013 - AACR
Molecular characterization of circulating tumor cells (CTC) from blood is technically
challenging because cells are rare and difficult to isolate. We developed a novel approach …

Immunomagnetic separation technologies

AELM Hoeppener, JF Swennenhuis… - … Residual Disease and …, 2012 - Springer
The largest difficulty one faces in the development of technology for detection of circulating
tumor cells (CTCs) is whether or not tumor cells are present in the blood and at what …

Evaluation of two different analytical methods for circulating tumor cell detection in peripheral blood of patients with primary breast cancer

BAS Jaeger, J Jueckstock… - BioMed research …, 2014 - Wiley Online Library
Background. Evidence is accumulating that circulating tumor cells (CTC) out of peripheral
blood can serve as prognostic marker not only in metastatic but also in early breast cancer …

[HTML][HTML] Circulating tumor cells detection in patients with early breast cancer using MACS immunomagnetic flow cytometry

N Karimi, M Oloomi, Z Orafa - Avicenna Journal of Medical …, 2020 - ncbi.nlm.nih.gov
Background: Circulating Tumor Cells (CTCs) detection in peripheral blood of epithelial
cancer patients is an indicator of the presence of primary tumors and metastasis. The CTC …

[HTML][HTML] Detection and prognostic significance of circulating tumour cells in patients with metastatic breast cancer according to immunohistochemical subtypes

DJE Peeters, PJ Van Dam… - British journal of …, 2014 - nature.com
Background: The enumeration of circulating tumour cells (CTCs) with the EpCAM-based
CellSearch system has prognostic significance in patients with metastatic breast cancer …