Involvement of p90 ribosomal S6 kinase in termination of cell cycle arrest during development of Artemia-encysted embryos

JQ Dai, XJ Zhu, FQ Liu, JH Xiang, H Nagasawa… - Journal of Biological …, 2008 - ASBMB
Artemia has evolved a unique developmental pattern of encysted embryos to cope with
various environmental threats. Cell divisions totally cease during the preemergence …

Two p90 ribosomal S6 kinase isoforms are involved in the regulation of mitotic and meiotic arrest in Artemia

RB Duan, L Zhang, DF Chen, F Yang, JS Yang… - Journal of Biological …, 2014 - ASBMB
There are multiple isoforms of p90 ribosomal S6 kinase (RSK), which regulate diverse
cellular functions such as cell growth, proliferation, maturation, and motility. However, the …

p90 ribosomal S6 kinase 1 (RSK1) isoenzyme specifically regulates cytokinesis progression

HJ Nam, IJ Lee, SH Jang, CD Bae, SJ Kwak, JH Lee - Cellular Signalling, 2014 - Elsevier
The p90 ribosomal S6 kinase family (RSK1–4) of Ser/Thr kinases is a downstream
component of the Ras-MAPK cascade responsible for regulating various cellular processes …

Identification and Characterization of a Ste20-Like Kinase in Artemia and Its Role in the Developmental Regulation and Resistance to Environmental Stress

R Zhou, YX Sun, WJ Yang, F Yang - Plos one, 2014 - journals.plos.org
Background To adapt to extreme environments, the crustacean Artemia has evolved two
alternative reproductive pathways. During ovoviviparous (direct) development, nauplius …

Down-regulation of RpS21, a putative translation initiation factor interacting with P40, produces viable minute imagos and larval lethality with overgrown hematopoietic …

I Török, D Herrmann-Horle, I Kiss, G Tick… - … and Cellular Biology, 1999 - Taylor & Francis
Down-regulation of the Drosophila ribosomal protein S21 gene (rpS21) causes a dominant
weak Minute phenotype and recessively produces massive hyperplasia of the hematopoietic …

Inhibition of ERK‐MAP kinase signaling by RSK during Drosophila development

M Kim, JH Lee, H Koh, SY Lee, C Jang… - The EMBO …, 2006 - embopress.org
Although p90 ribosomal S6 kinase (RSK) is known as an important downstream effector of
the ribosomal protein S6 kinase/extracellular signal‐regulated kinase (Ras/ERK) pathway …

Cloning and characterization of Xenopus Rsk2, the predominant p90 Rsk isozyme in oocytes and eggs

RR Bhatt, JE Ferrell - Journal of Biological Chemistry, 2000 - ASBMB
The 90-kDa ribosomal S6 kinases, the p90 Rsks, are a family of intracellular
serine/threonine protein kinases distinguished by two distinct kinase domains. Rsks are …

Targeted disruption of p70s6k defines its role in protein synthesis and rapamycin sensitivity

H Kawasome, P Papst, S Webb… - Proceedings of the …, 1998 - National Acad Sciences
Here, we disrupted the p70 S6 kinase (p70s6k) gene in murine embryonic stem cells to
determine the role of this kinase in cell growth, protein synthesis, and rapamycin sensitivity …

Calmodulin inhibition rescues DBA models with ribosomal protein deficiency through reduction of RSK signaling

ER Macari, AM Taylor, D Raiser, K Siva, K McGrath… - Blood, 2016 - Elsevier
Ribosomal protein (RP) mutations are found in many diseases, including Diamond Blackfan
anemia (DBA), where defective erythropoiesis, craniofacial abnormalities and increased …

Localization and retention of p90 ribosomal S6 kinase 1 in the nucleus: implications for its function

X Gao, D Chaturvedi, TB Patel - Molecular biology of the cell, 2012 - Am Soc Cell Biol
Ribosomal S6 kinase 1 (RSK1) belongs to a family of proteins with two kinase domains.
Following activation in the cytoplasm by extracellular signal-regulated kinases (ERK1/2), it …