The α subunit of AMP‐activated protein kinase is critical for the metabolic success and tachyzoite proliferation of Toxoplasma gondii

X Yang, J Yang, M Lyu, Y Li, A Liu… - Microbial …, 2024 - Wiley Online Library
Toxoplasma gondii is a zoonotic parasite infecting humans and nearly all warm‐blooded
animals. Successful parasitism in diverse hosts at various developmental stages requires …

Treatment with AICAR inhibits blastocyst development, trophectoderm differentiation and tight junction formation and function in mice

MD Calder, NA Edwards, DH Betts… - MHR: Basic science of …, 2017 - academic.oup.com
STUDY QUESTION What is the impact of adenosine monophosphate-activated protein
kinase (AMPK) activation on blastocyst formation, gene expression, and tight junction …

Akt activity negatively regulates phosphorylation of AMP-activated protein kinase in the heart

S Kovacic, CLM Soltys, AJ Barr, I Shiojima… - Journal of Biological …, 2003 - ASBMB
In the heart, insulin stimulates a variety of kinase cascades and controls glucose utilization.
Because insulin is able to activate Akt and inactivate AMP-activated protein kinase (AMPK) …

Adenosine 5′-triphosphate activates nuclear translocation of mitogen-activated protein kinases leading to the induction of early growth response 1 and raf …

CJ Tai, SJ Chang, PCK Leung… - The Journal of Clinical …, 2004 - academic.oup.com
With the stimulation of many types of cell surface receptors, MAPKs are activated. We have
previously demonstrated an effect of extracellular ATP on ERKs and gonadotropin-induced …

Characterization of Arginine Kinase in the Barnacle Amphibalanus Amphitrite and Its Role in the Larval Settlement

G Zhang, GY Yan, XX Yang, YH Wong… - … Zoology Part B …, 2016 - Wiley Online Library
Energy metabolism is a key process in larval settlement of barnacles, but the underlying
molecular mechanisms remain ambiguous. Arginine kinase (AK) mainly participates in …

Cell-free assays to measure effects of regulatory ligands on AMPK

FA Fyffe, SA Hawley, A Gray, DG Hardie - AMPK: Methods and Protocols, 2018 - Springer
AMP-activated protein kinase (AMPK) is an energy sensor that is activated by increases in
the cellular AMP/ATP and ADP/ATP ratios by three mechanisms:(1) allosteric activation,(2) …

[HTML][HTML] Crosstalk between the AMP-activated kinase and insulin signaling pathways rescues murine blastocyst cells from insulin resistance

E Louden, MM Chi, KH Moley - Reproduction (Cambridge, England …, 2008 - ncbi.nlm.nih.gov
Maternal insulin resistance results in poor pregnancy outcomes. In vivo and in vitro
exposure of the murine blastocyst to high insulin or IGF-1 results in the down-regulation of …

The potential role of Annexin 3 in diapause embryo restart of Artemia sinica and in response to stress of low temperature

N Li, F Yao, H Huang, H Zhang… - Molecular …, 2019 - Wiley Online Library
Annexins are highly conserved and ubiquitous in various somatic cell types. They are
involved in membrane transport and a range of calcium‐regulated activities on the cell …

Implication and regulation of AMPK during physiological and pathological myeloid differentiation

A Jacquel, F Luciano, G Robert, P Auberger - International journal of …, 2018 - mdpi.com
AMP-activated protein kinase (AMPK) is a heterotrimeric serine/threonine kinase consisting
of the arrangement of various α β, and γ isoforms that are expressed differently depending …

AICAR induces phosphorylation of AMPK in an ATM-dependent, LKB1-independent manner

Y Sun, KE Connors, DQ Yang - Molecular and cellular biochemistry, 2007 - Springer
AMPK is an AMP-activated protein kinase that plays an important role in regulating cellular
energy homeostasis. Metabolic stress, such as heat shock and glucose starvation, causes …