Cell therapy as a strategy to minimize maintenance immunosuppression in solid organ transplant recipients

EK Geissler, JA Hutchinson - Current opinion in organ …, 2013 - journals.lww.com
Remarkable progress is being made in the implementation of novel cell-based
immunotherapeutics in solid organ transplantation studies. It is hoped that these new …

Cell therapy approaches aiming at minimization of immunosuppression in solid organ transplantation

F Fändrich - Current Opinion in Organ Transplantation, 2010 - journals.lww.com
Although transplantation tolerance is still on its way to be reliably accomplished in clinical
settings, use of well specified and functionally characterized cellular therapeutics with …

Cell therapy in solid organ transplantation

S Cai, A Chandraker - Current Gene Therapy, 2019 - ingentaconnect.com
Transplantation is the only cure for end-stage organ failure. Current immunosuppressive
drugs have two major limitations: 1) non antigen specificity, which increases the risk of …

Cell therapy for immunosuppression after kidney transplantation

C Morath, A Schmitt, M Zeier, M Schmitt… - … archives of surgery, 2015 - Springer
Purpose To give an overview over cell therapeutic approaches to immunosuppression in
clinical kidney transplantation. A focus is on myeloid suppressor cell therapy by mitomycin C …

[HTML][HTML] Regulatory cell therapy in organ transplantation: achievements and open questions

M Fortunato, K Morali, L Passeri, S Gregori - Frontiers in Immunology, 2021 - frontiersin.org
The effective development of innovative surgical applications and immunosuppressive
agents have improved remarkable advancements in solid organ transplantation. Despite …

Hematopoietic stem cells and solid organ transplantation

R Elahimehr, AT Scheinok, DB McKay - Transplantation reviews, 2016 - Elsevier
Solid organ transplantation provides lifesaving therapy for patients with end stage organ
disease. In order for the transplanted organ to survive, the recipient must take a lifelong …

[HTML][HTML] The ONE Study compares cell therapy products in organ transplantation: introduction to a review series on suppressive monocyte-derived cells

EK Geissler - Transplantation research, 2012 - Springer
Organ transplantation has evolved into a reliable lifesaving procedure where good organ
function is quickly restored by the transplant and, typically, the patient can return to an active …

Recent immunomodulatory strategies in transplantation

A Ebrahimi, F Rahim - Immunological investigations, 2014 - Taylor & Francis
Despite preservation methods, surgical procedures, current immunosuppressive therapy
regimens advances, organ transplantation is accompanied with a poor long-term survival …

[HTML][HTML] Cell therapy in organ transplantation: our experience on the clinical translation of regulatory T cells

N Safinia, N Grageda, C Scottà, S Thirkell… - Frontiers in …, 2018 - frontiersin.org
Solid organ transplantation is the treatment of choice for patients with end-stage organ
dysfunction. Despite improvements in short-term outcome, long-term outcome is suboptimal …

Immunosuppressive therapy in allograft transplantation: from novel insights and strategies to tolerance and challenges

A Ebrahimi, SA Hosseini, F Rahim - Central European Journal of …, 2014 - termedia.pl
Abstract immunosuppression therapy is the key to successful post-transplantation outcomes.
The need for ideal immunosuppression became durable maintenance of long-term graft …