For scientific, ethical and economic reasons, experiments involving animals should be
appropriately designed, correctly analysed and transparently reported. This increases the …

Improving the reproducibility of biomedical research is a major challenge. Transparent and
accurate reporting is vital to this process; it allows readers to assess the reliability of the …

Over the last two decades, awareness of the negative repercussions of flaws in the planning,
conduct and reporting of preclinical research involving experimental animals has been …

There is widespread concern about the quality, reproducibility and translatability of studies
involving research animals. Although there are a number of reporting guidelines available …

Systematic reviews are generally regarded by professionals in the field of evidence-based
medicine as the highest level of medical evidence, and they are already standard practice …

There are important scientific, legal and ethical reasons for optimising the quality of animal
research and testing. Concerns about the reproducibility and translatability of animal studies …

The scientific literature of laboratory animal research is replete with papers reporting poor
reproducibility of results as well as failure to translate results to clinical trials in humans. This …

Before starting a new animal experiment, thorough analysis of previously performed
experiments is essential from a scientific as well as from an ethical point of view. The method …

Whole Animal Experiments Should Be More Like Human Randomized Controlled Trials |
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In the last decade the number of bioscience journals has increased enormously. The
emergence of open access journals has further revolutionized the publication process …