[HTML][HTML] Similar hypercoagulable state and thrombosis risk in type I and type III protein S-deficient individuals from families with mixed type I/III protein S deficiency
E Castoldi, LFA Maurissen, D Tormene, L Spiezia… - …, 2010 - ncbi.nlm.nih.gov
Background Protein S, which circulates in plasma in both free and bound forms, is an
anticoagulant protein that stimulates activated protein C and tissue factor pathway inhibitor …
anticoagulant protein that stimulates activated protein C and tissue factor pathway inhibitor …
Genetic and phenotypic analysis of a large (122-member) protein S–deficient kindred provides an explanation for the familial coexistence of type I and type III plasma …
RE Simmonds, B Zöller, H Ireland… - Blood, The Journal …, 1997 - ashpublications.org
Protein S deficiency is a known risk factor for thrombosis. The coexistence of phenotypic
type I (reduction in total and free antigen) and type III (reduction in free antigen only) protein …
type I (reduction in total and free antigen) and type III (reduction in free antigen only) protein …
Protein S type III deficiency is no risk factor for venous and arterial thromboembolism in 168 thrombophilic families: a retrospective study
EJ Libourel, I Bank, NJGM Veeger… - Blood coagulation & …, 2005 - journals.lww.com
Free protein S rather than total protein S levels are currently measured to detect inherited
protein S deficiency. Because type III (free protein S) deficiency is still not established as risk …
protein S deficiency. Because type III (free protein S) deficiency is still not established as risk …
Poor relationship between phenotypes of protein S deficiency and mutations in the protein S alpha gene
J Hermida, EM Faioni… - Thrombosis and …, 1999 - thieme-connect.com
By single strand conformational polymorphism, nucleotide sequencing and enzyme
restriction, we analyzed the protein S α gene in 17 protein S-deficient probands and in their …
restriction, we analyzed the protein S α gene in 17 protein S-deficient probands and in their …
Difference in absolute risk of venous and arterial thrombosis between familial protein S deficiency type I and type III. Results from a family cohort study to assess the …
JLP Brouwer, NJGM Veeger, W Schaaf… - British journal of …, 2005 - Wiley Online Library
Hereditary protein S (PS) deficiency type I is an established risk factor for venous
thromboembolism. Contradictionary data on type III deficiency suggests a difference in risk …
thromboembolism. Contradictionary data on type III deficiency suggests a difference in risk …
Regulation of coagulation by protein S
E Castoldi, TM Hackeng - Current opinion in hematology, 2008 - journals.lww.com
Regulation of coagulation by protein S : Current Opinion in Hematology Regulation of
coagulation by protein S : Current Opinion in Hematology Log in or Register Subscribe to …
coagulation by protein S : Current Opinion in Hematology Log in or Register Subscribe to …
Identification of 19 protein S gene mutations in patients with phenotypic protein S deficiency and thrombosis. Protein S Study Group
RE Simmonds, H Ireland, G Kunz, DA Lane - 1996 - ashpublications.org
Protein S is a protein C-dependent and independent inhibitor of the coagulation cascade.
Deficiency of protein S is an established risk factor for venous thromboembolism. We have …
Deficiency of protein S is an established risk factor for venous thromboembolism. We have …
Inherited protein S deficiency: clinical manifestations and laboratory findings in 63 patients
M Gouault-Heilmann, C Leroy-Matheron, M Levent - Thrombosis research, 1994 - Elsevier
To further characterize inherited heterozygous protein S (PS) deficiencies, we studied 63
patients belonging to 33 families. Diagnosis of PS deficiency was based on protein S activity …
patients belonging to 33 families. Diagnosis of PS deficiency was based on protein S activity …
Identification of eight point mutations in protein S deficiency type I–analysis of 15 pedigrees
PH Reitsma, E Gómez, SR Poort… - Thrombosis and …, 1995 - thieme-connect.com
We describe molecular genetic studies of 15 patients with protein S deficiency type I (ie
reduced total protein S antigen). All the exons of the PROS 1 gene were analyzed both by …
reduced total protein S antigen). All the exons of the PROS 1 gene were analyzed both by …
New quantitative total protein S-assay system for diagnosing protein S type II deficiency: clinical application of the screening system for protein S type II deficiency
T Tsuda, X Jin, H Tsuda, M Ieko… - Blood coagulation & …, 2012 - journals.lww.com
Venous thromboembolism (VTE) incidence is rising rapidly in Japan with lifestyle
westernization and aging. Deficiency of protein S, an important blood coagulation regulator …
westernization and aging. Deficiency of protein S, an important blood coagulation regulator …
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