Differentiation of embryonic stem cells to cardiomyocytes on electrospun nanofibrous substrates

MP Prabhakaran, LG Mobarakeh, D Kai… - … Research Part B …, 2014 - Wiley Online Library
The potential of pluripotent embryonic stem cells (ESCs) isolated from the inner mass of
blastocysts are investigated for its ability to differentiate on biocompatible electrospun …

Robust fabrication of composite 3D scaffolds with tissue-specific bioactivity: A proof-of-concept Study

MK Krishnamoorthi, U Sarig, L Baruch… - ACS Applied Bio …, 2020 - ACS Publications
The basic requirement of any engineered scaffold is to mimic the native tissue extracellular
matrix (ECM). Despite substantial strides in understanding the ECM, scaffold fabrication …

Direct hydrogel encapsulation of pluripotent stem cells enables ontomimetic differentiation and growth of engineered human heart tissues

P Kerscher, IC Turnbull, AJ Hodge, J Kim, D Seliktar… - Biomaterials, 2016 - Elsevier
Human engineered heart tissues have potential to revolutionize cardiac development
research, drug-testing, and treatment of heart disease; however, implementation is limited by …

[HTML][HTML] Cardiogenic differentiation of mesenchymal stem cells on elastomeric poly (glycerol sebacate)/collagen core/shell fibers

R Ravichandran, JR Venugopal… - World journal of …, 2013 - ncbi.nlm.nih.gov
AIM: To facilitate engineering of suitable biomaterials to meet the challenges associated with
myocardial infarction. METHODS: Poly (glycerol sebacate)/collagen (PGS/collagen) …

Influence of conductive polymer doping on the viability of cardiac progenitor cells

A Gelmi, MK Ljunggren, M Rafat… - Journal of Materials …, 2014 - pubs.rsc.org
Cardiac tissue engineering via the use of stem cells is the future for repairing impaired heart
function that results from a myocardial infarction. Developing an optimised platform to …

The cardiomyogenic differentiation of rat mesenchymal stem cells on silk fibroin–polysaccharide cardiac patches in vitro

MC Yang, SS Wang, NK Chou, NH Chi, YY Huang… - Biomaterials, 2009 - Elsevier
Polysaccharides and proteins profoundly impact the development and growth of tissues in
the natural extra-cellular matrix (ECM). To mimic a natural ECM, polysaccharides were …

Cardiogel: a nano-matrix scaffold with potential application in cardiac regeneration using mesenchymal stem cells

R Santhakumar, P Vidyasekar, RS Verma - PLoS One, 2014 - journals.plos.org
3-Dimensional conditions for the culture of Bone Marrow-derived Stromal/Stem Cells
(BMSCs) can be generated with scaffolds of biological origin. Cardiogel, a cardiac fibroblast …

Understanding the cellular responses based on low-density electrospun fiber networks

H Tang, B Yi, X Wang, Y Shen, Y Zhang - Materials Science and …, 2021 - Elsevier
Fibers produced from electrospinning are well-known to be extremely fine with diameters
ranging from tens of nanometers to a few microns. Such ultrafine fibers not only allow for …

Impact of setup orientation on blend electrospinning of poly-ε-caprolactone-gelatin scaffolds for vascular tissue engineering

S Suresh, O Gryshkov… - The International journal …, 2018 - journals.sagepub.com
Introduction: This article explores the effect of horizontal and vertical setups on blend
electrospinning with two polymers having vastly different properties–poly-ε-caprolactone …

A conductive cell-delivery construct as a bioengineered patch that can improve electrical propagation and synchronize cardiomyocyte contraction for heart repair

S Chen, MH Hsieh, SH Li, J Wu, RD Weisel… - Journal of Controlled …, 2020 - Elsevier
Cardiac tissue engineering is of particular importance in the combination of contracting cells
with a biomaterial scaffold, which serves as a cell-delivery construct, to replace …