Like other arthropod-borne viruses (arboviruses), mosquito-borne dengue virus (DENV) is
maintained in an alternating cycle of replication in arthropod and vertebrate hosts. The trade …

The emergence of mosquito-borne RNA viruses, such as West Nile virus (WNV), is facilitated
by genetically complex virus populations within hosts. Here, we determine whether WNV …

The alternating host cycle and persistent vector infection may constrain the evolution of
arboviruses. To test this hypothesis, eastern equine encephalitis virus was passaged in BHK …

Mosquito-borne alphaviruses, which replicate alternately and obligately in mosquitoes and
vertebrates, appear to experience lower rates of evolution than do many RNA viruses that …

Due to their error-prone replication, RNA viruses typically exist as a diverse population of
closely related genomes, which is considered critical for their fitness and adaptive potential …

Mosquitoes are haematophagous vectors for hundreds of pathogenic viruses that are
aetiological agents of human diseases. In nature, mosquito-borne viruses maintain a …

The high replication and mutation rates of RNA viruses can result in the emergence of new
epidemic variants. Thus, the ability to follow host-specific evolutionary trajectories of viruses …

The four dengue virus (DENV) serotypes (DENV serotype 1 [DENV-1] to DENV-4) are
transmitted by Aedes aegypti and A. albopictus mosquitoes, causing up to 390 million DENV …

Background It is known that insects and crustaceans can carry simultaneous, active
infections of two or more viruses without showing signs of disease, but it was not clear …

Recent advances in virus detection strategies and deep sequencing technologies have
enabled the identification of a multitude of new viruses that persistently infect mosquitoes but …