Increase in α‐CGRP and GAP‐43 in aged motoneurons: A study of peptides, growth factors, and ChAT mRNA in the lumbar spinal cord of senescent rats with …

H Johnson, K Mossberg, ULF Arvidsson… - Journal of …, 1995 - Wiley Online Library
Sprague‐Dawley rats develop progressive motor dysfunctions during the third year of life.
We use this as a model to examine possible neuronal mechanism (s) that may cause motor …

Regulatory effects of trophic factors on expression and distribution of CGRP and GAP‐43 in rat motoneurons

F Piehl, H Hammarberg, T Hökfelt… - Journal of …, 1998 - Wiley Online Library
Trophic factors play important roles for the regulation of several motoneuron characteristics.
In this report, we have studied the effects of different trophic factors on the regulation of two …

Reciprocal age-related changes in GAP-43/B-50, substance P and calcitonin gene-related peptide (CGRP) expression in rat primary sensory neurones and their …

M Hukkanen, LAM Platts, SA Corbett, S Santavirta… - Neuroscience …, 2002 - Elsevier
Age-related changes in the expression of the growth associated protein GAP-43/B-50, and
the neuropeptides substance P and calcitonin gene-related peptide (CGRP) were …

GAP‐43, aFGF, CCK and α‐and β‐CGRP in rat spinal motoneurons subjected to axotomy and/or dorsal root severance

F Piehl, U Arvidsson, H Johnson… - European Journal of …, 1993 - Wiley Online Library
The mRNA levels for growth‐associated protein 43 (GAP‐43), acidic fibroblast growth factor
(aFGF), α and β‐calcitonin gene‐related peptide (CGRP), cholecystokinin (CCK) and …

Decreased immunoreactive (IR) calcitonin gene-related peptide correlates with sprouting of IR-peptidergic and serotonergic neuronal processes in spinal cord and …

YQ Zhang, LL Vacca-Galloway - Brain research, 1992 - Elsevier
The Wobbler mouse possesses an inherited form of motoneuron disease that expresses
itself most dramatically in the forelimebs. Previous immunocytochemical (ICC) studies have …

Upregulation of GFRα‐1 and c‐ret in primary sensory neurons and spinal motoneurons of aged rats

E Bergman, S Kullberg, Y Ming… - Journal of neuroscience …, 1999 - Wiley Online Library
Aging is associated with a decline in neuromuscular and somatosensory functions. Senile
muscle atrophy, considered to be of neurogenic origin, is prevalent, and sensory thresholds …

Transganglionic response of GAP-43 in the gracile nucleus to sciatic nerve injury in young and aged rats

S Ohara, LN Beaudet, RE Schmidt - Brain research, 1995 - Elsevier
Sciatic nerve axotomy induces the transganglionic expression of the growth associated
protein GAP-43 and neuropeptide Y (NPY) in lumbar DRG projections to the gracile nucleus …

Increased expression of the growth‐associated protein 43 gene in the sensorimotor cortex of the macaque monkey after lesioning the lateral corticospinal tract

N Higo, Y Nishimura, Y Murata, T Oishi… - Journal of …, 2009 - Wiley Online Library
To investigate the neural basis for functional recovery of the cerebral cortex following spinal
cord injury, we measured the expression of growth‐associated protein 43 (GAP‐43), which …

GAP 43-like immunoreactivity in normal adult rat sciatic nerve, spinal cord, and motoneurons: axonal transport and effect of spinal cord transection

JY Li, A Kling-Petersen, A Dahlström - Neuroscience, 1993 - Elsevier
Using immunofluorescence and cytofluorimetric scanning techniques in the rat, the fast
anterograde and retrograde axonal transport of growth-associated protein-43-like …

Light and electron microscopic localization of B‐50 (GAP43) in the rat spinal cord during transganglionic degenerative atrophy and regeneration

E Knyihar‐Csillik, B Csillik… - Journal of neuroscience …, 1992 - Wiley Online Library
Crush or transection of a peripheral nerve is known to induce transganglionic degenerative
atrophy (TDA) in the segmentally related, ipsilateral Rolando substance of the spinal cord …