[HTML][HTML] Polymorphisms in the HTR2A and HTR3A Genes Contribute to Pain in TMD Myalgia

S Louca Jounger, N Christidis… - Frontiers in Oral …, 2021 - frontiersin.org
Background: The aim of this study was to investigate if single nucleotide polymorphisms
(SNPs) related to monoaminergic neurotransmission, in particular the serotonergic pathway …

The association of genetic polymorphisms in serotonin transporter and catechol‐O‐methyltransferase on temporomandibular disorders and anxiety in adolescents

JA Brancher, PP Spada, MN Meger… - Journal of oral …, 2019 - Wiley Online Library
Background Temporomandibular disorder (TMD) is a multifactorial condition involving
environmental, psychological and genetic factors. Objective The aim of this case‐control …

Polymorphisms in COMT, ADRB2 and HTR1A genes are associated with temporomandibular disorders in individuals with other arthralgias

LL Bonato, V Quinelato, PC de Felipe Cordeiro… - CRANIO®, 2019 - Taylor & Francis
Objective: To evaluate the association between polymorphisms in genes and comorbid
presence of arthralgias and TMD. Methods: This is a case-control study. The groups formed …

Influence of genetic polymorphisms on mechanical pain sensitivity and endogenous pain modulation of trigeminal and spinal areas

FFC Soares, DMAO Ferreira… - Journal of Oral …, 2023 - Wiley Online Library
Background Previous evidence indicates significant association between genetic
polymorphisms and phenotypes related to pain sensitivity in patients with …

TMD pain is partly heritable. A systematic review of family studies and genetic association studies

CM Visscher, F Lobbezoo - Journal of oral rehabilitation, 2015 - Wiley Online Library
The aim of this study was to describe the current knowledge on the role of heritability in TMD
pain through a systematic review of the literature, including familiar aggregation studies and …

The association of T102C (rs6313) polymorphism in the 5-HT2A receptor gene with temporomandibular disorders and anxiety in a group of Turkish population

Ö Ekici, ES Arıkan Söylemez - CRANIO®, 2024 - Taylor & Francis
Objective To investigate the relationship between T102C (rs6313) polymorphism in the 5-
hydroxytryptamine receptor-2A (5HTR2A) gene and temporomandibular disorder (TMD) and …

Association of HTR2A polymorphisms with chronic widespread pain and the extent of musculoskeletal pain: Results from two population‐based cohorts

BI Nicholl, KL Holliday, GJ Macfarlane… - Arthritis & …, 2011 - Wiley Online Library
Objective The aim of the current study was to investigate whether genetic variation in genes
across the serotoninergic system is associated with chronic widespread pain (CWP) and the …

Association of oral behaviours and psychological factors with selected genotypes in pain‐related TMD

M Zlendić, E Vrbanović, M Tomljanović… - Oral …, 2024 - Wiley Online Library
Objectives To investigate frequency of single nucleotide polymorphisms (SNPs) in pain‐
related temporomandibular disorders (TMDp) and to determine whether specific SNPs …

Genomics and the new perspectives for temporomandibular disorders

CB Meloto, PO Serrano, MC Ribeiro-DaSilva… - Archives of oral …, 2011 - Elsevier
The field of temporomandibular disorders (TMD) is experiencing significant changes in
terms of aetiology and treatment. Researchers and clinicians are becoming increasingly …

[HTML][HTML] Potential genetic risk factors for chronic TMD: genetic associations from the OPPERA case control study

SB Smith, DW Maixner, JD Greenspan, R Dubner… - The Journal of …, 2011 - Elsevier
Genetic factors play a role in the etiology of persistent pain conditions, putatively by
modulating underlying processes such as nociceptive sensitivity, psychological well-being …