Molecular mechanisms of Plasmodium falciparum placental adhesion: Microreview

A Scherf, B Pouvelle, PA Buffet, J Gysin - Cellular microbiology, 2001 - Wiley Online Library
In natural Plasmodium falciparum infections, parasitized erythrocytes (PEs) circulate in the
peripheral blood for a period corresponding roughly to the first part of the erythrocytic life …

[HTML][HTML] Insight into Antigenic Diversity of VAR2CSA-DBL5ε Domain from Multiple Plasmodium falciparum Placental Isolates

S Gnidehou, L Jessen, S Gangnard, C Ermont… - PLoS …, 2010 - journals.plos.org
Background Protection against pregnancy associated malaria (PAM) is associated with high
levels of anti-VAR2CSA antibodies. This protection is obtained by the parity dependent …

[HTML][HTML] Characterization of anti-var2CSA-PfEMP1 cytoadhesion inhibitory mouse monoclonal antibodies

M Avril, B Gamain, C Lépolard, N Viaud, A Scherf… - Microbes and …, 2006 - Elsevier
Pregnancy-associated malaria (PAM) is associated with the massive sequestration of
erythrocytes infected with CSA-binding parasites in the placenta. Natural protective immunity …

[HTML][HTML] Disruption of Var2csa Gene Impairs Placental Malaria Associated Adhesion Phenotype

NK Viebig, E Levin, S Dechavanne, SJ Rogerson… - PloS one, 2007 - journals.plos.org
Infection with Plasmodium falciparum during pregnancy is one of the major causes of
malaria related morbidity and mortality in newborn and mothers. The complications of …

Characterization of the molecular mechanisms involved in severe malaria pathogenesis

AS Nunes da Silva - 2016 - theses.fr
Résumé L'importante virulence de P. Falciparum a été reliée à la capacité du parasite à
adhérer aux cellules endothéliales de la microvasculature ou aux syncytiotrophoblastes …

[HTML][HTML] Plasmodium falciparum population dynamics in a cohort of pregnant women in Senegal

J Guitard, P Andersen, C Ermont, S Gnidehou, N Fievet… - Malaria Journal, 2010 - Springer
Background Pregnant women acquire protective antibodies that cross-react with
geographically diverse placental Plasmodium falciparum isolates, suggesting that surface …

VAR2CSA-Mediated Host Defense Evasion of Plasmodium falciparum Infected Erythrocytes in Placental Malaria

A Cheˆne - Immunity to Parasitic Infections in Pregnancy, 2022 - books.google.com
Over 30 million women living in P. falciparum endemic areas are at risk of developing
malaria during pregnancy every year. Placental malaria is characterized by massive …

[HTML][HTML] VAR2CSA Signatures of High Plasmodium falciparum Parasitemia in the Placenta

E Rovira-Vallbona, I Monteiro, A Bardaji… - PloS one, 2013 - journals.plos.org
Plasmodium falciparum infected erythrocytes (IE) accumulate in the placenta through the
interaction between Duffy-binding like (DBL) domains of parasite-encoded ligand VAR2CSA …

Transcribed var Genes Associated with Placental Malaria in MalawianWomen

MF Duffy, A Caragounis, R Noviyanti… - Infection and …, 2006 - Am Soc Microbiol
Determining the diversity of PfEMP1 sequences expressed by Plasmodium falciparum-
infected erythrocytes isolated from placentas is important for attempts to develop a …

Parasite adhesion and immune evasion in placental malaria

JG Beeson, JC Reeder, SJ Rogerson, GV Brown - TRENDS in Parasitology, 2001 - cell.com
Parasite sequestration in the placenta is a key feature of infection by Plasmodium falciparum
during pregnancy and is associated with severe adverse outcomes for both mother and …