Towards the use of baculovirus as a gene therapy vector.
L Pieroni, N La Monica - Current Opinion in Molecular Therapeutics, 2001 - europepmc.org
The use of baculovirus vectors for gene expression in mammalian cells is in continuous
expansion. These vectors do not replicate in mammalian cells, do not cause a cytopathic …
expansion. These vectors do not replicate in mammalian cells, do not cause a cytopathic …
Baculovirus vectors for gene therapy
YC Hu - Advances in virus research, 2006 - Elsevier
Since the discovery that baculoviruses can efficiently transduce mammalian cells,
baculoviruses have been extensively studied as potential vectors for both in vitro and in vivo …
baculoviruses have been extensively studied as potential vectors for both in vitro and in vivo …
Baculovirus-mediated gene delivery into mammalian cells does not alter their transcriptional and differentiating potential but is accompanied by early viral gene …
Gene delivery to neural cells is central to the development of transplantation therapies for
neurological diseases. In this study, we used a baculovirus derived from the domesticated …
neurological diseases. In this study, we used a baculovirus derived from the domesticated …
Baculoviruses mediate efficient gene expression in a wide range of vertebrate cells
KJ Airenne, KE Makkonen, AJ Mähönen… - Viral vectors for gene …, 2011 - Springer
Baculovirus expression vector system (BEVS) is well known as a feasible and safe
technology to produce recombinant (re-) proteins in a eukaryotic milieu of insect cells …
technology to produce recombinant (re-) proteins in a eukaryotic milieu of insect cells …
Baculoviral vectors for gene delivery: a review
YC Hu - Current gene therapy, 2008 - ingentaconnect.com
Baculovirus has emerged as a novel vector for in vivo and in vitro gene delivery. In addition,
the applications of baculovirus-mediated gene transfer have been explosively expanded to …
the applications of baculovirus-mediated gene transfer have been explosively expanded to …
Baculovirus-mediated gene delivery into mammalian cells
RV Merrihew, TA Kost, JP Condreay - … to Mammalian Cells: Volume 2: Viral …, 2004 - Springer
A relatively recent advance in the use of recombinant baculoviruses is their use for delivery
of genes and genetic elements into mammalian cells. Baculovirus vectors retrofitted with …
of genes and genetic elements into mammalian cells. Baculovirus vectors retrofitted with …
Baculovirus as a tool for gene delivery and gene therapy
C Ono, T Okamoto, T Abe, Y Matsuura - Viruses, 2018 - mdpi.com
Based on its ability to express high levels of protein, baculovirus has been widely used for
recombinant protein production in insect cells for more than thirty years with continued …
recombinant protein production in insect cells for more than thirty years with continued …
In vivo application and tracking of baculovirus
KJ Airenne, KE Makkonen, AJ Mahonen… - Current gene …, 2010 - ingentaconnect.com
Baculoviruses are safe and high-capacity vectors for gene delivery which have matured from
the initial successful experiments performed in liver cells into convenient tools to transduce …
the initial successful experiments performed in liver cells into convenient tools to transduce …
Baculoviruses in gene therapy and personalized medicine
This review will outline the role of baculoviruses in gene therapy and future potential in
personalized medicine. Baculoviruses are a safe, non-toxic, non-integrative vector with a …
personalized medicine. Baculoviruses are a safe, non-toxic, non-integrative vector with a …
Editorial [Hot topic: Baculovirus: A Promising Vector for Gene Therapy?(Guest Editor: Yu-Chen Hu)]
YC Hu - Current gene therapy, 2010 - ingentaconnect.com
The widely used viral gene therapy vectors include retrovirus, lentivirus, adenovirus and
adeno-associated virus, which have proven to be clinically valuable in numerous trials …
adeno-associated virus, which have proven to be clinically valuable in numerous trials …