Towards the use of baculovirus as a gene therapy vector.

L Pieroni, N La Monica - Current Opinion in Molecular Therapeutics, 2001 - europepmc.org
The use of baculovirus vectors for gene expression in mammalian cells is in continuous
expansion. These vectors do not replicate in mammalian cells, do not cause a cytopathic …

Baculovirus vectors for gene therapy

YC Hu - Advances in virus research, 2006 - Elsevier
Since the discovery that baculoviruses can efficiently transduce mammalian cells,
baculoviruses have been extensively studied as potential vectors for both in vitro and in vivo …

Baculovirus-mediated gene delivery into mammalian cells does not alter their transcriptional and differentiating potential but is accompanied by early viral gene …

C Kenoutis, RC Efrose, L Swevers, AA Lavdas… - Journal of …, 2006 - Am Soc Microbiol
Gene delivery to neural cells is central to the development of transplantation therapies for
neurological diseases. In this study, we used a baculovirus derived from the domesticated …

Baculoviruses mediate efficient gene expression in a wide range of vertebrate cells

KJ Airenne, KE Makkonen, AJ Mähönen… - Viral vectors for gene …, 2011 - Springer
Baculovirus expression vector system (BEVS) is well known as a feasible and safe
technology to produce recombinant (re-) proteins in a eukaryotic milieu of insect cells …

Baculoviral vectors for gene delivery: a review

YC Hu - Current gene therapy, 2008 - ingentaconnect.com
Baculovirus has emerged as a novel vector for in vivo and in vitro gene delivery. In addition,
the applications of baculovirus-mediated gene transfer have been explosively expanded to …

Baculovirus-mediated gene delivery into mammalian cells

RV Merrihew, TA Kost, JP Condreay - … to Mammalian Cells: Volume 2: Viral …, 2004 - Springer
A relatively recent advance in the use of recombinant baculoviruses is their use for delivery
of genes and genetic elements into mammalian cells. Baculovirus vectors retrofitted with …

Baculovirus as a tool for gene delivery and gene therapy

C Ono, T Okamoto, T Abe, Y Matsuura - Viruses, 2018 - mdpi.com
Based on its ability to express high levels of protein, baculovirus has been widely used for
recombinant protein production in insect cells for more than thirty years with continued …

In vivo application and tracking of baculovirus

KJ Airenne, KE Makkonen, AJ Mahonen… - Current gene …, 2010 - ingentaconnect.com
Baculoviruses are safe and high-capacity vectors for gene delivery which have matured from
the initial successful experiments performed in liver cells into convenient tools to transduce …

Baculoviruses in gene therapy and personalized medicine

S Schaly, M Ghebretatios, S Prakash - Biologics: Targets and …, 2021 - Taylor & Francis
This review will outline the role of baculoviruses in gene therapy and future potential in
personalized medicine. Baculoviruses are a safe, non-toxic, non-integrative vector with a …

Editorial [Hot topic: Baculovirus: A Promising Vector for Gene Therapy?(Guest Editor: Yu-Chen Hu)]

YC Hu - Current gene therapy, 2010 - ingentaconnect.com
The widely used viral gene therapy vectors include retrovirus, lentivirus, adenovirus and
adeno-associated virus, which have proven to be clinically valuable in numerous trials …