Baculoviruses are safe and high-capacity vectors for gene delivery which have matured from
the initial successful experiments performed in liver cells into convenient tools to transduce …

In 1982 E. coli produced human insulin, the world's first recombinant DNA drug, was
approved by the FDA. Since this historical event, remarkable progress has been made in …

The baculovirus/insect cell expression system is best known, and used, as a research tool
for the production of recombinant proteins often requiring post-translational modifications …

Gene delivery to neural cells is central to the development of transplantation therapies for
neurological diseases. In this study, we used a baculovirus derived from the domesticated …

Baculovirus is extensively utilized as an excellent tool for production of recombinant protein
in insect cells. Baculovirus infects insects in nature and is non-pathogenic to humans. In …

Functional expression of recombinant proteins has become a routine, but critical tool in
modern molecular biology. Since their introduction, the use of baculovirus vectors to …

Baculoviruses are enveloped, insect-specific viruses with large double-stranded DNA
genomes. Among all the baculovirus species, Autographa californica multiple …

Baculoviruses continue to serve as workhorse vectors for the high-level expression of
eukaryotic genes in insect cells; however, numerous researchers are also finding novel uses …

Various methods have been developed to transfer and express genes in mammalian cells.
Each method, whether virally, non-virally, or physically-based, has unique favorable …

The baculovirus expression system has been used extensively for the expression of
recombinant proteins in insect cells. Recently, recombinant baculovirus vectors engineered …