This review will outline the role of baculoviruses in gene therapy and future potential in
personalized medicine. Baculoviruses are a safe, non-toxic, non-integrative vector with a …

The use of baculovirus vectors for gene expression in mammalian cells is in continuous
expansion. These vectors do not replicate in mammalian cells, do not cause a cytopathic …

Baculoviruses are arthropod-specific, enveloped viruses with circular, supercoiled double-
stranded deoxyribonucleic acid genomes. While many viruses are studied to seek solutions …

Baculovirus infects insects in nature and is non-pathogenic to humans, but can transduce a
broad range of mammalian and avian cells. Thanks to the biosafety, large cloning capacity …

Baculovirus has emerged as a novel vector for in vivo and in vitro gene delivery. In addition,
the applications of baculovirus-mediated gene transfer have been explosively expanded to …

Baculoviruses are enveloped, insect-specific viruses with large double-stranded DNA
genomes. Among all the baculovirus species, Autographa californica multiple …

Since the discovery that baculoviruses can efficiently transduce mammalian cells,
baculoviruses have been extensively studied as potential vectors for both in vitro and in vivo …

Baculovirus expression vector system (BEVS) is well known as a feasible and safe
technology to produce recombinant (re-) proteins in a eukaryotic milieu of insect cells …

Baculovirus is an insect virus which has been used for more than thirty years for production
of recombinant proteins in insect cells. However, baculovirus can also be harnessed for …

The widely used viral gene therapy vectors include retrovirus, lentivirus, adenovirus and
adeno-associated virus, which have proven to be clinically valuable in numerous trials …