Traditionally, four groups of factors have been identified in the etiology of
temporomandibular disorder (TMD): anatomical variation in the masticatory system; …

AIMS:(1) To examine the heritability of TMD pain and of neck pain; and (2) to estimate the
potential overlap in genetic and environmental factors influencing TMD pain and neck pain …

BACKGROUND: Genetic variations represented as single nucleotide polymorphisms (SNPs)
vary across the world population. This genetic polymorphism (such as SNPs) plays an …

Abstract Genetic variants in MTHFD1 (5, 10-methylenetetrahydrofolate dehydrogenase/5, 10-
methenyltetrahydrofolate cyclohydrolase/10-formyltetrahydrofolate synthetase), an important …

Objectives: Nonsyndromic cleft lip and palate (NSCLP) is genetically distinct from those with
syndromic clefts, and accounts for~ 70% of cases with Oral clefts. Folate, or vitamin B9, is an …

Objective: To assess whether a relationship existed between the T102C polymorphism of 5‐
HT2A receptor gene and temporomandibular dysfunction. Methods: Sixty‐three patients with …

Aims: To evaluate the association between catechol-O-methyltransferase (COMT) gene
polymorphisms and temporomandibular disorders (TMD), TMD pain, psychosocial …

Background: Folate is essential for DNA synthesis, repair, and methylation. Polymorphisms
in genes associated with folate metabolism may alter these processes and, consequently …

Papers in this issue investigate when and how putative risk factors influence development of
first-onset, painful temporomandibular disorder (TMD). The results represent first findings …

Objective The aim of this study was to assess the correlation of inflammatory and pain genes
polymorphisms with the presence of temporomandibular disorder (TMD) patients and with …