Role of inflammatory and pain genes polymorphisms in temporomandibular disorder and pressure pain sensitivity

LMSP Fiamengui, BDA Furquim… - Archives of Oral …, 2020 - Elsevier
Objective The aim of this study was to assess the correlation of inflammatory and pain genes
polymorphisms with the presence of temporomandibular disorder (TMD) patients and with …

Influence of TNF-α-308 G/A gene polymorphism on temporomandibular disorder

BDA Furquim, LMSP Flamengui, CEP Repeke… - American Journal of …, 2016 - Elsevier
Introduction Tumor necrosis factor alpha (TNF-α) levels are significantly upregulated in the
synovial fluid of patients with temporomandibular joint disorder (TMD). The TNF-α influences …

Influence of genetic polymorphisms on mechanical pain sensitivity and endogenous pain modulation of trigeminal and spinal areas

FFC Soares, DMAO Ferreira… - Journal of Oral …, 2023 - Wiley Online Library
Background Previous evidence indicates significant association between genetic
polymorphisms and phenotypes related to pain sensitivity in patients with …

Cytokine biomarkers and chronic pain: association of genes, transcription, and circulating proteins with temporomandibular disorders and widespread palpation …

GD Slade, MS Conrad, L Diatchenko, NU Rashid… - Pain, 2011 - Elsevier
For reasons unknown, temporomandibular disorder (TMD) can manifest as localized pain or
in conjunction with widespread pain. We evaluated relationships between cytokines and …

[HTML][HTML] Genetic variants associated with development of TMD and its intermediate phenotypes: the genetic architecture of TMD in the OPPERA prospective cohort …

SB Smith, E Mir, E Bair, GD Slade, R Dubner… - The Journal of …, 2013 - Elsevier
Genetic risk factors are believed to combine with environmental exposures and contribute to
the risk of developing temporomandibular disorder (TMD). In this prospective cohort study …

Association of temporomandibular disorders with pain sensitivity: a cohort study

J Knuutila, J Kivipuro, R Näpänkangas… - … Journal of Pain, 2022 - Wiley Online Library
Background Pain related to temporomandibular disorders (TMD) can be linked with multiple
site pain (MSP), and may associate with increased pain sensitivity, more frequently among …

Association of oral behaviours and psychological factors with selected genotypes in pain‐related TMD

M Zlendić, E Vrbanović, M Tomljanović… - Oral …, 2024 - Wiley Online Library
Objectives To investigate frequency of single nucleotide polymorphisms (SNPs) in pain‐
related temporomandibular disorders (TMDp) and to determine whether specific SNPs …

Genetic influence on treatment outcomes in patients with pain‐related temporomandibular disorders

M Zlendić, E Vrbanović, KG Trošelj… - Journal of oral …, 2024 - Wiley Online Library
Abstract Background Single nucleotide polymorphisms (SNPs) may influence pain
susceptibility and impact treatment response in pain‐related temporomandibular disorders …

[HTML][HTML] Potential genetic risk factors for chronic TMD: genetic associations from the OPPERA case control study

SB Smith, DW Maixner, JD Greenspan, R Dubner… - The Journal of …, 2011 - Elsevier
Genetic factors play a role in the etiology of persistent pain conditions, putatively by
modulating underlying processes such as nociceptive sensitivity, psychological well-being …

Shared genetics of temporomandibular disorder pain and neck pain: results of a twin study

CM Visscher, MJ Schouten, L Ligthart… - Journal of oral & facial …, 2018 - research.vu.nl
AIMS:(1) To examine the heritability of TMD pain and of neck pain; and (2) to estimate the
potential overlap in genetic and environmental factors influencing TMD pain and neck pain …