Studies from this laboratory, employing a hairless mouse model, have indicated that a
polyunsaturated fatty acid source rich in omega‐3 (n− 3) fatty acid (FA) inhibits ultraviolet …

Because arachidonic acid-derived eicosanoids are potent modulators of hyperproliferation
and inflammation during skin tumor promotion with the phorbol ester, 12-0 …

Dietary sources of lipids containing predominantly n‐3 or n‐6 fatty acids (FA) have been
examined for effect upon several potential pathophysiologic parameters. Epidermal, plasma …

To investigate the effects of two levels of dietary corn oil on tumorigenesis, semipurified diets
containing 5% or 10% corn oil were fed during the promotion stage of a mouse skin …

Dietary n-6 polyunsaturated fatty acids (PUFAs) promote rat mammary cancer while n-3
PUFAs are inhibitory. The purpose of this study was to determine whether the fats exert their …

The effects of dietary stearidonic acid (18∶ 4n− 3) on inflammatory mediator release in
whole blood and splenocytes was investigated in Balb/c mice, and the effects were …

The effect of fish oil (FO, given in the form of MaxEPA) rich in n-3 fatty acids and evening
primrose oil (EPO) rich in n-6 fatty acids on two-stage skin carcinogenesis in mice was …

The production of inflammatory mediators, relevant to (auto) immune diseases and chronic
inflammatory conditions, can be modulated by dietary intake of n‐3 and n‐6 long chain …

Increasing levels of dietary corn oil have been correlated with inhibition of 12‐O‐
tetradecanoyl‐phorbol‐13‐acetate‐(TPA) promoted skin tumetigenesis in mice (Leyton et al …

Omega-6 (ω-6) polyunsaturated fatty acids (PUFA), abundant in the Western diet, are
precursors for a number of key mediators of inflammation including the 2-series of …