The advent of induced pluripotent stem cells (iPSCs) revolutionized human genetics by
allowing us to generate pluripotent cells from easily accessible somatic tissues. This …

Human iPS cells have been generated using a diverse range of tissues from a variety of
donors using different reprogramming vectors. However, these cell lines are heterogeneous …

Epigenetic reprogramming is a critical event in the generation of induced pluripotent stem
cells (iPSCs). Here, we determined the DNA methylation profiles of 22 human iPSC lines …

The ability to reprogram somatic cells to induced pluripotent stem cells (iPSCs) has
revolutionized the field of regenerative medicine. However, recent studies on the genetic …

Induced pluripotent stem cells (iPSCs) are generated by direct reprogramming of somatic
cells and hold great promise for novel therapies. However, several studies have reported …

Human pluripotent stem cells (hPSCs) are potential sources of cells for modeling disease
and development, drug discovery, and regenerative medicine. However, it is important to …

Reprogramming of somatic cells into induced Pluripotent Stem Cells (iPSCs) is a major leap
towards personalised approaches to disease modelling and cell-replacement therapies …

Induced pluripotent stem cells (iPSCs) are an essential tool for studying cellular
differentiation and cell types that are otherwise difficult to access. We investigated the use of …

Variability in induced pluripotent stem cell (iPSC) lines remains a concern for disease
modeling and regenerative medicine. We have used RNA-sequencing analysis and linear …

Induced pluripotent stem cells (iPSCs) show variable methylation patterns between lines,
some of which reflect aberrant differences relative to embryonic stem cells (ESCs). To …