Oxidative stress is now recognized as accountable for redox regulation involving reactive
oxygen species (ROS) and reactive nitrogen species (RNS). Its role is pivotal for the …

Oxidative stress is typically reported in neurodegenerative diseases. Although the
mechanisms underlying this condition are not completely understood, the brain appears …

Oxidative stress is proposed as a regulatory element in ageing and various neurological
disorders. The excess of oxidants causes a reduction of antioxidants, which in turn produce …

Reactive species play an important role in physiological functions. Overproduction of
reactive species, notably reactive oxygen (ROS) and nitrogen (RNS) species along with the …

Mitochondria is one of the main source of oxidative stress (ROS), as it utilizes the oxygen for
the energy production. ROS and RNS are normally generated by tightly regulated enzymes …

Neurodegenerative disorders constitute a substantial proportion of neurological diseases
with significant public health importance. The pathophysiology of neurodegenerative …

The continuous production and efflux of reactive oxygen/nitrogen species from endogenous
and exogenous sources can damage biological molecules and initiate a cascade of events …

Reactive oxygen species are constantly produced in aerobic organisms as by-products of
normal oxygen metabolism and include free radicals such as superoxide anion (O 2−) and …

Neurodegenerative diseases affect not only the life quality of aging populations, but also
their life spans. All forms of neurodegenerative diseases have a massive impact on the …

Age is the main risk factor for a number of human diseases, including neurodegenerative
disorders such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral …