The usefulness of human induced pluripotent stem cells (hiPSCs) in research and
therapeutic applications highly relies on their genomic integrity and stability. Many …

Studies using high-resolution genome-wide approaches have recently reported that
genomic and epigenomic alterations frequently accumulate in human pluripotent cells …

Because of their somatic cell origin, human induced pluripotent stem cells (HiPSCs) are
assumed to carry a normal diploid genome, and adaptive chromosomal aberrations have …

Human induced pluripotent stem cells (hiPSCs) have the potential to differentiate virtually
into any cell type in unlimited quantities. Therefore, they are ideal for in vitro tissue modeling …

Ten years after the initial generation of induced pluripotent stem cells (hiPSCs) from human
tissues, their potential is no longer questioned, with over 15000 publications listed on …

Human embryonic stem cells (hESCs) can undergo unlimited self-renewal and are
pluripotent, retaining the ability to differentiate into all cell types in the body. As a renewable …

Human pluripotent stem cells (hPSCs) are being increasingly utilized worldwide in
investigating human development, and modeling and discovering therapies for a wide range …

Genetic instability in human induced pluripotent stem cells: Classification of causes and
possible safeguards Page 1 www.landesbioscience.com Cell Cycle 4603 Cell Cycle 9:23 …

Human induced pluripotent stem cells (hiPSCs) and human embryonic stem cells (hESCs)
are promising candidate cell sources for regenerative medicine. However, despite the …

Mutations in human induced pluripotent stem cells (iPSCs) pose a risk for their clinical use
due to preferential reprogramming of mutated founder cell and selection of mutations during …