Role of procalcitonin in managing adult patients with respiratory tract infections

P Schuetz, DN Amin, JL Greenwald - Chest, 2012 - Elsevier
Respiratory infections remain the most common reason why patients seek medical care in
ambulatory and hospital settings, and they are the most frequent precursor of sepsis. In light …

Procalcitonin in respiratory disease: use as a biomarker for diagnosis and guiding antibiotic therapy

AW Creamer, AE Kent, M Albur - Breathe, 2019 - Eur Respiratory Soc
Procalcitonin (PCT) is a peptide measurable in serum which becomes elevated in response
to bacterial infection. Multiple trials have explored the safety and efficacy of using PCT as a …

How to best use procalcitonin to diagnose infections and manage antibiotic treatment

P Schuetz - Clinical Chemistry and Laboratory Medicine (CCLM), 2023 - degruyter.com
Objectives Procalcitonin (PCT) is a host-response biomarker that has shown clinical value
for assessing the likelihood of bacterial infections and guiding antibiotic treatment …

Meta-analysis and systematic review of procalcitonin-guided therapy in respiratory tract infections

H Li, YF Luo, TS Blackwell, CM Xie - Antimicrobial agents and …, 2011 - Am Soc Microbiol
Circulating procalcitonin (PCT) is a biomarker that can be used in diagnosing bacterial
infections. We performed a quantitative meta-analysis of available randomized controlled …

Procalcitonin-guided antibiotic treatment of respiratory tract infections in a primary care setting: are we there yet?

R Aabenhus, JUS Jensen - Primary Care Respiratory Journal, 2011 - nature.com
Clinical signs of infection do not allow for correct identification of bacterial and viral aetiology
in acute respiratory infections. A valid tool to assist the clinician in identifying patients who …

Procalcitonin-guided diagnosis and antibiotic stewardship revisited

R Sager, A Kutz, B Mueller, P Schuetz - BMC medicine, 2017 - Springer
Several controlled clinical studies have evaluated the potential of the infection biomarker
procalcitonin (PCT) to improve the diagnostic work-up of patients with bacterial infections …

Procalcitonin monitoring as a guide for antimicrobial therapy: a review of current literature

EW Covington, MZ Roberts… - … : The Journal of Human …, 2018 - Wiley Online Library
Effective antimicrobial stewardship practices are increasingly essential to best utilize the
current arsenal of antimicrobials for the shortest necessary duration to minimize the …

Streamlining antibiotic therapy with procalcitonin protocols: consensus and controversies

S Haubitz, B Mueller, P Schuetz - Expert review of respiratory …, 2013 - Taylor & Francis
Accumulating evidence supports procalcitonin (PCT) as an accurate surrogate biomarker for
likelihood and severity of bacterial infections. In community-acquired pneumonia and other …

Procalcitonin to guide antibiotic decision making

A Branche, O Neeser, B Mueller… - Current opinion in …, 2019 - journals.lww.com
Inclusion of PCT into antibiotic stewardship algorithms has the potential to improve the
diagnostic and therapeutic management of patients presenting with respiratory illnesses and …

Procalcitonin for guidance of antibiotic therapy

P Schuetz, W Albrich, M Christ-Crain… - Expert review of anti …, 2010 - Taylor & Francis
Procalcitonin is a surrogate biomarker for estimating the likelihood of a bacterial infection.
Procalcitonin-guided initiation and termination of antibiotic therapy is a novel approach …