Identification and characterization of SAP25, a novel component of the mSin3 corepressor complex
Y Shiio, DW Rose, R Aur, S Donohoe… - … and cellular biology, 2006 - Taylor & Francis
The transcriptional corepressor mSin3 is associated with histone deacetylases (HDACs) and
is utilized by many DNA-binding transcriptional repressors. We have cloned and …
is utilized by many DNA-binding transcriptional repressors. We have cloned and …
The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3
MG Guenther, ORR Barak… - Molecular and cellular …, 2001 - Am Soc Microbiol
Repression of gene transcription is linked to regulation of chromatin structure through
deacetylation of core histone amino-terminal tails. This action is mediated by histone …
deacetylation of core histone amino-terminal tails. This action is mediated by histone …
Identification and characterization of three new components of the mSin3A corepressor complex
TC Fleischer, UJ Yun, DE Ayer - Molecular and cellular biology, 2003 - Taylor & Francis
The mSin3A corepressor complex contains 7 to 10 tightly associated polypeptides and is
utilized by many transcriptional repressors. Much of the corepressor function of mSin3A …
utilized by many transcriptional repressors. Much of the corepressor function of mSin3A …
CHD1 associates with NCoR and histone deacetylase as well as with RNA splicing proteins
HH Tai, M Geisterfer, JC Bell, M Moniwa… - Biochemical and …, 2003 - Elsevier
CHD1 is one of a family of nuclear proteins containing two chromodomains, a SWI/SNF-like
helicase/ATPase domain and a DNA binding domain. We found that CHD1 co …
helicase/ATPase domain and a DNA binding domain. We found that CHD1 co …
The histone deacetylase-3 complex contains nuclear receptor corepressors
Acetylation and deacetylation of nucleosomal histones have profound effects on gene
transcription in all eukaryotes. In humans, three highly homologous class I and four class II …
transcription in all eukaryotes. In humans, three highly homologous class I and four class II …
[HTML][HTML] Continuous and widespread roles for the Swi–Snf complex in transcription
SR Biggar, GR Crabtree - The EMBO journal, 1999 - embopress.org
Chromatin presents a significant obstacle to transcription, but two means of overcoming its
repressive effects, histone acetylation and the activities of the Swi–Snf complex, have been …
repressive effects, histone acetylation and the activities of the Swi–Snf complex, have been …
Histone deacetylase 1 can repress transcription by binding to Sp1
A Doetzlhofer, H Rotheneder, G Lagger… - … and cellular biology, 1999 - Taylor & Francis
The members of the Sp1 transcription factor family can act as both negative and positive
regulators of gene expression. Here we show that Sp1 can be a target for histone …
regulators of gene expression. Here we show that Sp1 can be a target for histone …
Functional domains of histone deacetylase-3
Post-translational modifications of histones, in general, and acetylation/deacetylation, in
particular, can dramatically alter gene expression in eukaryotic cells. In humans, four highly …
particular, can dramatically alter gene expression in eukaryotic cells. In humans, four highly …
Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation
Accessibility of the genome to DNA-binding transcription factors is regulated by proteins that
control the acetylation of amino-terminal lysine residues on nucleosomal histones …
control the acetylation of amino-terminal lysine residues on nucleosomal histones …
Diverse nucleosome site-selectivity among histone deacetylase complexes
Histone acetylation regulates chromatin structure and gene expression and is removed by
histone deacetylases (HDACs). HDACs are commonly found in various protein complexes to …
histone deacetylases (HDACs). HDACs are commonly found in various protein complexes to …