[引用][C] Role of HTLV‐1 proviral DNA load and clonality in the development of adult T‐cell leukemia/lymphoma in asymptomatic carriers

A Okayama, S Stuver, M Matsuoka… - … journal of cancer, 2004 - Wiley Online Library
Human T-lymphotropic virus type 1 (HTLV-1) is the causative agent for adult T-cell
leukemia/lymphoma (ATL). 1–3 Only a small proportion of HTLV-1 carriers eventually …

Natural course of HTLV-1 carriers with monoclonal proliferation of T lymphocytes (“pre-ATL”) in a 20-year follow-up study

Y Imaizumi, M Iwanaga, K Tsukasaki, T Hata… - Blood, 2005 - ashpublications.org
Previously we reported that asymptomatic human T-cell lymphotropic virus type 1 (HTLV-1)
carriers with a monoclonal proliferation of HTLV-1–infected T cells (“pre–adult T-cell …

Modelling the risk of adult T‐cell leukemia/lymphoma in persons infected with human T‐lymphotropic virus type I

EL Murphy, B Hanchard, JP Figueroa… - … journal of cancer, 1989 - Wiley Online Library
Adult T‐cell leukemia/lymphoma (ATL), a malignancy of mature CD4‐positive lymphocytes,
has been etiologically linked to the human retrovirus HTLV‐I. Although a long latent period …

How does HTLV-1 cause adult T-cell leukaemia/lymphoma (ATL)?

CRM Bangham, L Ratner - Current opinion in virology, 2015 - Elsevier
Highlights•Molecular mechanisms of HTLV-1 oncogenesis.•Innate and acquired immune
response to HTLV-1.•Clonality of HTLV-1 in vivo.•We bring together the host and viral factors …

HTLV-1 replication and adult T cell leukemia development

CZ Giam - Viruses and Human Cancer: From Basic Science to …, 2021 - Springer
Human T-cell leukemia virus type 1 (HTLV-1) is a complex human delta retrovirus that
infects an estimated 10–20 million people worldwide (Gessain and Cassar 2012). HTLV-1 …

Human T-lymphotropic virus type 1 infection

K Tsukasaki, P Koeffler, M Tomonaga - Best Practice & Research Clinical …, 2000 - Elsevier
Human T-cell lymphotropic virus type-1 (HTLV-1) is aetiologically associated with adult T-
cell leukaemia/lymphoma (ATL). HTLV-1 infection can also lead to various non-malignant …

Trends in HTLV‐1 prevalence and incidence of adult T‐cell leukemia/lymphoma in Nagasaki, Japan

Y Koga, M Iwanaga, M Soda, N Inokuchi… - Journal of medical …, 2010 - Wiley Online Library
Most previous studies aimed at estimating the number of human T‐cell leukemia virus type‐
1 (HTLV‐1) carriers in endemic areas have been based on seroprevalence rates in blood …

Human T-cell leukemia virus type I (HTLV-1) proviral load and disease progression in asymptomatic HTLV-1 carriers: a nationwide prospective study in Japan

M Iwanaga, T Watanabe, A Utsunomiya… - Blood, The Journal …, 2010 - ashpublications.org
Definitive risk factors for the development of adult T-cell leukemia (ATL) among
asymptomatic human T-cell leukemia virus type I (HTLV-1) carriers remain unclear …

High HTLV‐I proviral DNA level associated with abnormal lymphocytes in peripheral blood from asymptomatic carriers

N Tachibana, A Okayama, S Ishihara… - … journal of cancer, 1992 - Wiley Online Library
The level of proviral DNA in peripheral blood mononuclear cells from a representative group
of asymptomatic HTLV‐I carriers in Miyazaki district, an HTLV‐I endemic area in Japan, was …

[图书][B] Prevention of human T-cell lymphotropic virus type 1 infection and adult T-cell leukemia/lymphoma

M Yoshimitsu, Y White, N Arima - 2014 - Springer
Adult T-cell leukemia/lymphoma (ATLL) is a highly aggressive peripheral T-cell malignancy
that develops after long-term chronic infection with human T-cell lymphotropic virus type-1 …