T-cell control by human T-cell leukemia/lymphoma virus type 1

G Franchini, R Fukumoto, JR Fullen - International journal of hematology, 2003 - Springer
Human T-cell leukemia/lymphoma virus type 1 (HTLV-1) causes neoplastic transformation of
human T-cells in a small number of infected individuals several years from infection …

Human T lymphotropic virus type-I and adult T-cell leukemia in Japan

K Yamaguchi, T Watanabe - International journal of hematology, 2002 - Springer
HTLV-I is the first retrovirus to be associated directly with human malignancy. In ATL-
endemic areas, the rate of HTLV-I carriers is high. Both HTLV-I and ATL have been shown to …

Role of HTLV-I in development of non-Hodgkin lymphoma in Jamaica and Trinidad and Tobago

A Manns, FR Cleghorn, RT Falk, P Hartge, J Benichou… - The Lancet, 1993 - Elsevier
Human T-cell lymphotropic virus type I (HTLV-I) has been implicated in the aetiology of adult
T-cell leukaemia/lymphoma in Japan and elsewhere, particularly the Caribbean. We have …

Evolution of retrovirus-infected premalignant T-cell clones prior to adult T-cell leukemia/lymphoma diagnosis

AG Rowan, R Dillon, A Witkover… - Blood, The Journal …, 2020 - ashpublications.org
Adult T-cell leukemia/lymphoma (ATL) is an aggressive hematological malignancy caused
by human T-cell leukemia virus type-1 (HTLV-1). ATL is preceded by decades of chronic …

[HTML][HTML] Switching and loss of cellular cytokine producing capacity characterize in vivo viral infection and malignant transformation in human T- lymphotropic virus …

H Kagdi, MA Demontis, JC Ramos, GP Taylor - PLoS pathogens, 2018 - journals.plos.org
Adult T-cell leukaemia/lymphoma (ATL) arises from chronic non-malignant human T
lymphotropic virus type-1 (HTLV-1) infection which is characterized by high plasma pro …

[HTML][HTML] HTLV-1 propels untransformed CD4+ lymphocytes into the cell cycle while protecting CD8+ cells from death

D Sibon, AS Gabet, M Zandecki… - The Journal of …, 2006 - Am Soc Clin Investig
Human T cell leukemia virus type 1 (HTLV-1) infects both CD4+ and CD8+ lymphocytes, yet
it induces adult T cell leukemia/lymphoma (ATLL) that is regularly of the CD4+ phenotype …

[HTML][HTML] Adult T-cell leukemia: a review of epidemiological evidence

M Iwanaga, T Watanabe, K Yamaguchi - Frontiers in microbiology, 2012 - frontiersin.org
Adult T-cell leukemia (ATL) is an aggressive T-cell malignancy caused by human T-cell
leukemia virus type I (HTLV-1) infection and often occurs in HTLV-1-endemic areas, such as …

Distinct transformation tropism exhibited by human T lymphotropic virus type 1 (HTLV-1) and HTLV-2 is the result of postinfection T cell clonal expansion

P Kannian, H Yin, R Doueiri, MD Lairmore… - Journal of …, 2012 - Am Soc Microbiol
Human T lymphotropic virus type 1 (HTLV-1) and HTLV-2 are related but pathogenically
distinct viruses. HTLV-1 mainly causes adult T cell leukemia, while HTLV-2 is not associated …

Assessment of HTLV-1 proviral load, LAT, BIM, c-FOS and RAD51 gene expression in adult T cell leukemia/lymphoma

S Ramezani, A Shirdel, H Rafatpanah… - Medical microbiology …, 2017 - Springer
Adult T cell leukemia/lymphoma (ATLL) is a life-threatening malignancy of HTLV-1 infected
Th lymphocytes. In the present study host–virus interactions were investigated by …

Research and discovery of the first human cancer virus, HTLV-1

RC Gallo - Best Practice & Research Clinical Haematology, 2011 - Elsevier
Human T-cell lymphoma virus (HTLV)-1 was the first human retrovirus to be discovered. It
has been recognized as the cause of adult T-cell leukemia (ATL). In addition to giving a …