Transgene silencing, RNA interference, and the antiviral defense mechanism directed by small interfering RNAs

SW Ding - Phytopathology®, 2023 - Am Phytopath Society
One important discovery in plant pathology over recent decades is the natural antiviral
defense mechanism mediated by RNA interference (RNAi). In antiviral RNAi, virus infection …

[HTML][HTML] The potyviral suppressor of RNA silencing confers enhanced resistance to multiple pathogens

GJ Pruss, CB Lawrence, T Bass, QQ Li, LH Bowman… - Virology, 2004 - Elsevier
Helper component-protease (HC-Pro) is a plant viral suppressor of RNA silencing, and
transgenic tobacco expressing HC-Pro has increased susceptibility to a broad range of viral …

Double-stranded RNA binding may be a general plant RNA viral strategy to suppress RNA silencing

Z Mérai, Z Kerényi, S Kertész, M Magna… - Journal of …, 2006 - Am Soc Microbiol
In plants, RNA silencing (RNA interference) is an efficient antiviral system, and therefore
successful virus infection requires suppression of silencing. Although many viral silencing …

RNA interference: historical overview and significance

MK Montgomery - RNA Interference, Editing, and Modification: Methods …, 2004 - Springer
In the early 1990s, attempts to manipulate gene expression by researchers working in three
different fields resulted in unanticipated gene silencing. Rather than ignoring such results …

[HTML][HTML] Low temperature inhibits RNA silencing‐mediated defence by the control of siRNA generation

G Szittya, D Silhavy, A Molnár, Z Havelda… - The EMBO …, 2003 - embopress.org
Temperature dramatically affects plant–virus interactions. Outbreaks of virus diseases are
frequently associated with low temperature, while at high temperature viral symptoms are …

Small RNAs in plant immunity and virulence of filamentous pathogens

Y Qiao, R Xia, J Zhai, Y Hou, L Feng… - Annual Review of …, 2021 - annualreviews.org
Gene silencing guided by small RNAs governs a broad range of cellular processes in
eukaryotes. Small RNAs are important components of plant immunity because they …

Post-transcriptional gene silencing in plants

H Vaucheret, C Béclin, M Fagard - Journal of cell science, 2001 - journals.biologists.com
Post-transcriptional gene silencing (PTGS) in plants is an RNA-degradation mechanism that
shows similarities to RNA interference (RNAi) in animals. Indeed, both involve double …

[HTML][HTML] Silencing and innate immunity in plant defense against viral and non-viral pathogens

AS Zvereva, MM Pooggin - Viruses, 2012 - mdpi.com
The frontline of plant defense against non-viral pathogens such as bacteria, fungi and
oomycetes is provided by transmembrane pattern recognition receptors that detect …

The role of viruses in identifying and analyzing RNA silencing

DC Baulcombe - Annual Review of Virology, 2022 - annualreviews.org
Adaptive antiviral immunity in plants is an RNA-based mechanism in which small RNAs
derived from both strands of the viral RNA are guides for an Argonaute (AGO) nuclease. The …

Suppression of gene silencing: a general strategy used by diverse DNA and RNA viruses of plants

O Voinnet, YM Pinto… - Proceedings of the …, 1999 - National Acad Sciences
In transgenic and nontransgenic plants, viruses are both initiators and targets of a defense
mechanism that is similar to posttranscriptional gene silencing (PTGS). Recently, it was …