Discrepant diagnosis rate of array comparative genomic hybridization in thawed euploid blastocysts

AW Tiegs, B Hodes-Wertz, DH McCulloh… - Journal of assisted …, 2016 - Springer
Purpose Preimplantation genetic screening (PGS) and diagnosis (PGD) with euploid
embryo transfer is associated with improved implantation and live birth rates as compared to …

Pregnancy rates after pre-implantation genetic screening for aneuploidy are only superior when trophectoderm biopsy is performed on hatching embryos

S Singh, E Hobeika, ES Knochenhauer… - Journal of Assisted …, 2019 - Springer
Purpose In vitro fertilization with trophectoderm embryo biopsy and pre-implantation genetic
screening with comprehensive chromosomal screening (PGS-CCS) for aneuploidy is …

Rebiopsy and preimplantation genetic screening (PGS) reanalysis for embryos with an initial non-diagnostic result yields a euploid result in the majority of cases

SA Neal, EJ Forman, CR Juneau, J Morin… - Fertil …, 2017 - ivi-rmainnovation.com
OBJECTIVE: After PGS, a small percentage of embryo biopsies do not yield a result suitable
for a diagnosis. There are limited data regarding the efficacy of rebiopsying these embryos …

[HTML][HTML] Preimplantation genetic diagnosis for chromosomal rearrangements with the use of array comparative genomic hybridization at the blastocyst stage

C Christodoulou, A Dheedene, B Heindryckx… - Fertility and …, 2017 - Elsevier
Objective To establish the value of array comparative genomic hybridization (CGH) for
preimplantation genetic diagnosis (PGD) in embryos of translocation carriers in combination …

Non-invasive preimplantation genetic testing for putative mosaic blastocysts: a pilot study

X Li, Y Hao, D Chen, D Ji, W Zhu, X Zhu… - Human …, 2021 - academic.oup.com
STUDY QUESTION What is the potential of applying non-invasive preimplantation genetic
testing (niPGT) for chromosome abnormalities in blastocysts reported with a mosaic …

Day of trophectoderm biopsy and embryo quality are associated with outcomes following euploid embryo transfer

CE Gordon, A Lanes, A Thomas… - Journal of Assisted …, 2022 - Springer
Purpose To compare clinical outcomes following transfer of euploid blastocysts of varying
quality biopsied on day 5 versus day 6. Methods Retrospective cohort study to evaluate …

When next-generation sequencing-based preimplantation genetic testing for aneuploidy (PGT-A) yields an inconclusive report: diagnostic results and clinical …

SA Neal, L Sun, C Jalas, SJ Morin, TA Molinaro… - Journal of assisted …, 2019 - Springer
Purpose To describe diagnostic results following re-biopsy of blastocysts with inconclusive
results on preimplantation genetic screening for aneuploidy (PGT-A) and to evaluate the …

[HTML][HTML] Next generation sequencing for preimplantation genetic screening improves pregnancy outcomes compared with array comparative genomic hybridization in …

J Friedenthal, SM Maxwell, S Munné, Y Kramer… - Fertility and sterility, 2018 - Elsevier
Objective To evaluate whether the use of next generation sequencing (NGS) for
preimplantation genetic screening (PGS) in single thawed euploid embryo transfer (STEET) …

A greater number of euploid blastocysts in a given cohort predicts excellent outcomes in single embryo transfer cycles

S Morin, K Melzer-Ross, D McCulloh, J Grifo… - Journal of assisted …, 2014 - Springer
Purpose This multicentered retrospective study analyzed whether the quantity of euploid
blastocysts in a given cohort after comprehensive chromosomal screening can be used to …

Clinical outcomes after the transfer of blastocysts characterized as mosaic by high resolution Next Generation Sequencing-further insights

S Munné, F Spinella, J Grifo, J Zhang… - European journal of …, 2020 - Elsevier
Objective To determine the pregnancy outcome potential of euploid, mosaic and aneuploid
embryos. Design Retrospective study. Setting Reference genetics laboratories. Patient (s) …