Heat-producing beige/brite (brown-in-white) adipocytes in white adipose tissue have the
potential to suppress metabolic disease in mice and hold great promise for the treatment of …

The attractive tenet that recruitment and activation of brown adipose tissue (BAT) and
uncoupling protein 1 (UCP1) could counteract the development of obesity and its …

Obesity is characterized by an excess of white adipose tissue (WAT). Recent evidence has
demonstrated that WAT can change its phenotype to a brown-like adipose tissue known as …

Mitochondrial uncoupling proteins (UCPs) are transporters that are important for
thermogenesis. The net result of their activity is the exothermic movement of protons through …

Uncoupling protein (UCP) is expressed only in brown adipocytes and is responsible for the
unique thermogenic properties of this cell type. The novel brown preadipocyte cell line, HIB …

Presence of brown adipose tissue (BAT), characterized by the expression of the
thermogenic uncoupling protein 1 (UCP1), has recently been described in adult humans …

The mRNA expressions of UCP2 and UCP3, two newly described genes with high
sequence homology to the uncoupling protein UCP1 in brown adipose tissue (BAT), were …

Objective Classical ATP-independent non-shivering thermogenesis enabled by uncoupling
protein 1 (UCP1) in brown adipose tissue (BAT) is activated, but not essential for survival, in …

Mitochondrial uncoupling protein 1 (UCP1) is the crucial mechanistic component of heat
production in classical brown fat and the newly identified beige or brite fat. Thermogenesis …

During the past few years, there have been two major developments, if not revolutions, in the
field of energy balance and weight regulation. The first at the molecular level, which was …