Energy expenditure through brown adipose tissue thermogenesis contributes either to
maintenance of body temperature in a cold environment or to wasted food energy, ie cold …

Mitochondrial uncoupling proteins (UCPs) are transporters that are important for
thermogenesis. The net result of their activity is the exothermic movement of protons through …

Investigations of variations in metabolic efficiency and thermogenesis have a short and
turbulent history. In small animals, non‐shivering thermogenesis and diet‐induced …

Uncoupling protein 1 (Ucp1) is the key component of β-adrenergically controlled
nonshivering thermogenesis in brown adipocytes. This process combusts stored and …

OBJECTIVE: In rodents, adaptive thermogenesis in response to cold exposure and high-fat
feeding is accomplished by the activation of the brown adipose tissue specific mitochondrial …

The cloning of the uncoupling protein (UCP) 1 homologs UCP2 and UCP3 has raised
considerable interest in the mechanism. The expression of UCP3 mainly in skeletal muscle …

Abstract Uncoupling protein 2 (UCP2) was discovered in 1997 and classified as an
uncoupling protein largely based on its homology of sequence with UCP1. Since its …

Massive overweight is an increasing health problem and underlies several complications
which in turn result in premature death. The mechanisms underlying the imbalance between …

Energy balance in animals is a metabolic state that exists when total body energy
expenditure equals dietary energy intake. Energy expenditure, or thermogenesis, can be …

Uncoupling protein-2 and-3 (UCP2 and UCP3) are mitochondrial proteins that show high
sequence homology with the brown adipocyte-specific UCP1. UCP1 induces heat …