LRRC3B gene is frequently epigenetically inactivated in several epithelial malignancies and inhibits cell growth and replication
Chromosome 3 specific NotI microarrays containing 180 NotI linking clones associated with
188 genes were hybridized to NotI representation probes prepared using matched …
188 genes were hybridized to NotI representation probes prepared using matched …
miR-142-5p promotes cervical cancer progression by targeting LMX1A through Wnt/β-catenin pathway
L Ke, Y Chen, Y Li, Z Chen, Y He, J Liu, Y Zhuang - Open Medicine, 2021 - degruyter.com
Background Previous work has shown that miR-142-5p in cervical cancer tissues increased
significantly compared with adjacent normal tissues. However, the function and the …
significantly compared with adjacent normal tissues. However, the function and the …
A model for co-expression pattern analysis of genes implicated in angiogenesis and tumour cell invasion in cervical cancer
PO Van Trappen, A Ryan, M Carroll, C Lecoeur… - British journal of …, 2002 - nature.com
To date, numerous genes have been identified which are involved in both tumour
neovascularisation (angiogenesis) and tumour cell invasion, and most of them are also …
neovascularisation (angiogenesis) and tumour cell invasion, and most of them are also …
Vascular endothelial growth factor (VEGF) up-regulates epidermal growth factor receptor (EGF-R) in cervical cancer in vitro: this action is mediated through HPV-E6 in …
RS Mathur, SP Mathur - Gynecologic oncology, 2005 - Elsevier
OBJECTIVES: Epidermal Growth Factor Receptor (EGF-R) up-regulation in cervical cancer
cells leads to an increase in cell proliferative Insulin-like Growth Factor II (IGF-II) and …
cells leads to an increase in cell proliferative Insulin-like Growth Factor II (IGF-II) and …
Overexpression of RRM2 is related to poor prognosis in oral squamous cell carcinoma
S Wang, XL Wang, ZZ Wu, QC Yang, HG Xiong… - Oral …, 2021 - Wiley Online Library
Abstract Objectives Ribonucleotide reductase M2 (RRM2) is a rate‐limiting enzyme involved
in DNA repair and synthesis. This study aimed to investigate the expression level …
in DNA repair and synthesis. This study aimed to investigate the expression level …
RRM2 regulates Bcl-2 in head and neck and lung cancers: a potential target for cancer therapy
MA Rahman, ARMR Amin, D Wang, L Koenig… - Clinical cancer …, 2013 - AACR
Purpose: Ribonucleotide reductase subunit M2 (RRM2) plays an active role in tumor
progression. Recently, we reported that depletion of RRM2 by systemic delivery of a …
progression. Recently, we reported that depletion of RRM2 by systemic delivery of a …
Expression of human papillomavirus type 16 E6 and E7 oncoproteins in primary foreskin keratinocytes is sufficient to alter the expression of angiogenic factors
E Toussaint-Smith, DB Donner, A Roman - Oncogene, 2004 - nature.com
Human papillomavirus (HPV) 16 is involved in causing cervical cancer. The E6 and E7
proteins of HPV 16 immortalize human keratinocytes and this is due, at least in part, to …
proteins of HPV 16 immortalize human keratinocytes and this is due, at least in part, to …
miR-211 regulates the expression of RRM2 in tumoral metastasis and recurrence in colorectal cancer patients with a k-ras gene mutation
CC Chang, CC Lin, CH Wang… - Oncology …, 2018 - spandidos-publications.com
Colorectal cancer (CRC) ranks as the third‑leading cause of cancer‑associated mortalities in
Taiwan. The expression of ribonucleotide reductase M2 (RRM2) and p53R2 is associated …
Taiwan. The expression of ribonucleotide reductase M2 (RRM2) and p53R2 is associated …
BRF2 is mediated by microRNA-409-3p and promotes invasion and metastasis of HCC through the Wnt/β-catenin pathway
JH Chang, BW Xu, D Shen, W Zhao, Y Wang… - Cancer Cell …, 2023 - Springer
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Its
invasiveness and ability to metastasize contributes to an extremely high patient mortality …
invasiveness and ability to metastasize contributes to an extremely high patient mortality …
[HTML][HTML] MiR-155-5p inhibits PDK1 and promotes autophagy via the mTOR pathway in cervical cancer
F Wang, S Shan, Y Huo, Z Xie, Y Fang, Z Qi… - The international journal …, 2018 - Elsevier
Cervical cancer is one of the most common malignant tumors and the leading cause of
cancer-related mortality in women. Persistent cervical infection by high-risk human …
cancer-related mortality in women. Persistent cervical infection by high-risk human …