A curcumin-sophorolipid nanocomplex inhibits Candida albicans filamentation and biofilm development

V Rajasekar, P Darne, A Prabhune, RYT Kao… - Colloids and Surfaces B …, 2021 - Elsevier
Candida albicans is an opportunistic fungal pathogen that is highly resistant to
contemporary antifungals, due to their biofilm lifestyle. The ability of C. albicans to invade …

[HTML][HTML] Inhibitory Effect of Sophorolipid on Candida albicans Biofilm Formation and Hyphal Growth

F Haque, M Alfatah, K Ganesan, MS Bhattacharyya - Scientific Reports, 2016 - nature.com
Candida albicans causes superficial and life-threatening systemic infections. These are
difficult to treat often due to drug resistance, particularly because C. albicans biofilms are …

[HTML][HTML] 3-Hydroxy coumarin demonstrates anti-biofilm and anti-hyphal efficacy against Candida albicans via inhibition of cell-adhesion, morphogenesis, and virulent …

TJ Sushmitha, M Rajeev, V Kathirkaman, S Shivam… - Scientific Reports, 2023 - nature.com
Candida albicans, a common fungus of human flora, can become an opportunistic pathogen
and causes invasive candidiasis in immunocompromised individuals. Biofilm formation is …

[HTML][HTML] In vitro and in vivo effects of suloctidil on growth and biofilm formation of the opportunistic fungus Candida albicans

B Zeng, J Li, Y Wang, P Chen, X Wang, J Cui, L Liu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
As the most frequent fungal pathogen in humans, Candida albicans can develop serious
drug resistance because its biofilms are resistant to most antifungal agents; this leads to an …

Anti-Biofilm Activity of Assamsaponin A, Theasaponin E1, and Theasaponin E2 against Candida albicans

Y Chen, Y Gao, Y Li, J Yin - International Journal of Molecular Sciences, 2024 - mdpi.com
Biofilm formation plays a crucial role in the pathogenesis of Candida albicans and is
significantly associated with resistance to antifungal agents. Tea seed saponins, a class of …

Novel mechanisms of surfactants against Candida albicans growth and morphogenesis

Q Yu, B Zhang, F Ma, C Jia, C Xiao, B Zhang… - Chemico-Biological …, 2015 - Elsevier
Candida albicans is a common opportunistic fungal pathogen, causing not only superficial
mucosal infections but also life-threatening systemic candidiasis in immune-compromised …

Terpenoids of plant origin inhibit morphogenesis, adhesion, and biofilm formation by Candida albicans

JS Raut, RB Shinde, NM Chauhan… - Biofouling, 2013 - Taylor & Francis
Biofilm-related infections caused by Candida albicans and associated drug resistant micro-
organisms are serious problems for immunocompromised populations. Molecules which can …

Antifungal and antibiofilm action of triphenylphosphonium-conjugated curcumin on Candida albicans: Efficacy and activity mechanisms

GKK Reddy, PH Kumar, AR Padmavathi… - International …, 2024 - Elsevier
Natural compounds and their derivatives have become the source of new generation
antimicrobials to address the growing concern of antimicrobial resistance. The polyphenols …

Synergistic antifungal effects of curcumin derivatives as fungal biofilm inhibitors with fluconazole

HH Dong, YH Wang, XM Peng, HY Zhou… - Chemical Biology & …, 2021 - Wiley Online Library
Lack of novel antifungal agents and severe drug resistance has led to high incidence and
associated mortality of invasive fungal infections. To tackle the challenges, novel antifungal …

[HTML][HTML] Purpurin Suppresses Candida albicans Biofilm Formation and Hyphal Development

PWK Tsang, H Bandara, WP Fong - PloS one, 2012 - journals.plos.org
A striking and clinically relevant virulence trait of the human fungal pathogen Candida
albicans is its ability to grow and switch reversibly among different morphological forms …