This book will be an introduction to bone metastases for orthopaedic surgeons. It covers the
basic principles of surgery in bone cancer; radiographic imaging of skeletal metastases; …

abstract Bone is a very common site for cancer metastasis and may be the only site of
metastasis in patients with breast cancer or prostate cancer. The exact incidence of bone …

In Germany and other European countries, cancer is the second most common cause of
death after cardiovascular disease. Although 5-year survival rates for several types of cancer …

The epidemiological and clinical importance of bone metastasis has long been recognized,
but the past decade has seen an explosion in the fields of bone biology and bone cancer …

The radionuclide bone scan is the most effective whole body screening test for bone
metastases. Conventional radiography, although relatively insensitive to the presence of …

Cancer is the second leading cause of death in the United States50, and it was estimated 1
that there would be 910,000 new cases here in 1985. Metastasis is one of the most serious …

Metastatic spread to bones frequently occurs in several types of cancer diseases, in
particular breast, prostate, and lung cancer. Infiltration of bone by tumour cells is a source of …

Introduction: Bone metastases are associated with increased morbidity and decreased
quality of life in patients with solid tumors. Identifying patients at increased risk of bone …

The mechanisms by which tumors metastasize to bone are complex. Upon the successful
establishment of metastatic deposits in the skeleton, detection of the disease becomes …

Although primary bone tumors are rare, metastatic tumors involving bone are common, and
their incidence increase with age. As many as 60 percent of cancer patients will be found to …