Solid tumors often metastasize into bones affecting quality of life and overall survival of
cancer patients. Despite improvement of diagnostic tools, the presence of bone metastases …

Bone is a frequent site of metastases and typically indicates a short-term prognosis in cancer
patients. Once cancer has spread to the bones it can rarely be cured, but often it can still be …

Overall bone metastasis (BM) was found upon autopsy in 271 (26.0%) of 1041 patients who
died due to malignant epithelial neoplasm at our hospital over the last 20 years. The …

Bone metastases are a late event in tumor progression, contributing to morbidity and
mortality and decreasing patient quality of life. Cancer colonization of the skeleton is …

The skeleton is the most common organ to be affected by metastatic cancer and the site of
disease that produces the greatest morbidity. Skeletal morbidity includes pain that requires …

Metastatic carcinoma is the most common malignancy of bone. The clinical presentation of
patients with skeletal metastasis is variable. The orthopedist may be asked to evaluate a …

The actual improvement of epidemiologic database collection concerning bone metastases
of solid tumors allows us to better understand the seriousness of this evolution, its human …

When one looks back over the history of man's efforts to understand and treat metastasis
and metastatic bone disease, the principal feature from today's perspective is the radical …

Bone metastases are a frequent and debilitating consequence for many tumors, of which
breast, lung, prostate, and kidney cancer are the most common. The dialog among cancer …

Alterations in bone architecture and mineral metabolism are common complications of
malignancy. Cancers such as breast, prostate, and lung can affect the skeleton either …