Objective To investigate the impact of introducing a rapid test as the first-line diagnostic test
for drug-sensitive tuberculosis in Cape Town, South Africa. Methods Xpert® MTB/RIF …

Background Tuberculosis represents a serious public health problem and a significant
diagnostic and therapeutic challenge worldwide. Molecular diagnostic techniques are …

Summary The Xpert MTB/RIF (Xpert) test is a novel automated molecular diagnostic recently
endorsed by the World Health Organization for rapid diagnosis of tuberculosis (TB) …

SETTING: The first national anti-tuberculosis drug resistance survey in Pakistan, a high
tuberculosis (TB) and low human immunodeficiency virus (HIV) burden country …

The commercially available line probe assay MTBDRplus 2.0 (Hain Lifescience, Nehren,
Germany) was evaluated for its ability to detect Mycobacterium tuberculosis complex …

Rapid progress has been made in the development of new diagnostic assays for
tuberculosis in recent years. New technologies have been developed and assessed, and …

INTRODUCTION: The Xpert® MTB/RIF assay is being implemented as a substitute for
sputum smear microscopy (SSM) in many low and high tuberculosis (TB) burden countries …

Drug-resistant tuberculosis is a substantial health-care concern worldwide. Despite culture-
based methods being considered the gold standard for drug susceptibility testing, molecular …

Introduction Globally, multidrug resistant tuberculosis (MDR-TB) remains underdiagnosed.
The Genotype MTBDR plus®, a rapid drug susceptibility testing (DST) assay used to detect …

Background Over the past several years, new diagnostic techniques have been developed
to allow for the rapid detection of multidrug resistant tuberculosis. The GenoType® MTBDR …