Which new diagnostics for tuberculosis, and when?

F Cobelens, S van den Hof, M Pai… - Journal of Infectious …, 2012 - academic.oup.com
Recently, new diagnostic tools for tuberculosis detection and resistance testing have
become available. The World Health Organization endorses new tuberculosis diagnostics …

GenoType MTBDRplus Assay for Rapid Detection of Multidrug Resistance in Mycobacterium tuberculosis: A Meta-Analysis

Y Bai, Y Wang, C Shao, Y Hao, Y Jin - PloS one, 2016 - journals.plos.org
Background There is an urgent demand for rapid and accurate drug-susceptibility testing for
the detection of multidrug-resistant tuberculosis. The GenoType MTBDR plus assay is a …

Availability and use of molecular microbiological and immunological tests for the diagnosis of tuberculosis in Europe

M Tebruegge, N Ritz, K Koetz, A Noguera-Julian… - PloS one, 2014 - journals.plos.org
Introduction Currently only limited data exist regarding the availability and clinical use of
molecular and immunological tests for tuberculosis (TB) in the European setting. Methods …

Bacteriophage assays for rifampicin resistance detection in Mycobacterium tuberculosis: updated meta-analysis

J Minion, M Pai - The International journal of tuberculosis and …, 2010 - ingentaconnect.com
OBJECTIVE: To update a previously reported meta-analysis of evidence regarding the
diagnostic accuracy and performance characteristics of commercial and non-commercial …

Xpert MTB/RIF and Xpert MTB/RIF Ultra assays for active tuberculosis and rifampicin resistance in children

AW Kay, LG Fernández, Y Takwoingi… - Cochrane Database …, 2020 - cochranelibrary.com
Background Every year, at least one million children become ill with tuberculosis and
around 200,000 children die. Xpert MTB/RIF and Xpert Ultra are World Health Organization …

Xpert MTB/RIF and Xpert MTB/RIF Ultra for pulmonary tuberculosis and rifampicin resistance in adults

JS Zifodya, I Schiller, N Dendukuri… - Cochrane Database …, 2019 - cochranelibrary.com
Background Xpert MTB/RIF (Xpert MTB/RIF) and Xpert MTB/RIF Ultra (Xpert Ultra), the
newest version, are the only World Health Organization (WHO)‐recommended rapid tests …

A commercial line probe assay for the rapid detection of rifampicin resistance in Mycobacterium tuberculosis: a systematic review and meta-analysis

M Morgan, S Kalantri, L Flores, M Pai - BMC infectious diseases, 2005 - Springer
Background Mycobacterium tuberculosis is a leading cause of death worldwide. In multi-
drug resistant tuberculosis (MDR-TB) infectiousness is frequently prolonged, jeopardizing …

Genotypic, phenotypic and clinical validation of GeneXpert in extra-pulmonary and pulmonary tuberculosis in India

UB Singh, P Pandey, G Mehta, AK Bhatnagar… - PloS one, 2016 - journals.plos.org
Background Newer molecular diagnostics have brought paradigm shift in early diagnosis of
tuberculosis [TB]. WHO recommended use of GeneXpert MTB/RIF [Xpert] for Extra …

Evaluation of seven tests for the rapid detection of multidrug-resistant tuberculosis in Uganda

F Bwanga, ML Joloba, M Haile… - The International journal …, 2010 - ingentaconnect.com
SETTINGS: National Tuberculosis (TB) Reference Laboratory and Department of Medical
Microbiology, College of Health Sciences, Makerere University, Kampala, Uganda …

Multicenter Noninferiority Evaluation of Hain GenoType MTBDRplus Version 2 and Nipro NTM+MDRTB Line Probe Assays for Detection of Rifampin and Isoniazid …

RR Nathavitharana, D Hillemann… - Journal of clinical …, 2016 - Am Soc Microbiol
Less than 30% of multidrug-resistant tuberculosis (MDR-TB) patients are currently
diagnosed, due to laboratory constraints. Molecular diagnostics enable rapid and simplified …