Assessing the benefits of FEIBA prophylaxis in haemophilia patients with inhibitors
LA Valentino - Haemophilia, 2010 - Wiley Online Library
Prophylaxis with concentrates of factor VIII has become the standard of care for patients with
severe haemophilia A because of its ability to prevent joint and other bleeding events …
severe haemophilia A because of its ability to prevent joint and other bleeding events …
FEIBA prophylaxis in haemophilia patients: a clinical update and treatment recommendations
D Perry, E Berntorp, C Tait, G Dolan, PA Holme… - …, 2010 - Wiley Online Library
In patients with severe haemophilia and inhibitors, regular factor VIII inhibitor bypassing
activity (FEIBA) prophylaxis has been shown to reduce the frequency of bleeding by up to …
activity (FEIBA) prophylaxis has been shown to reduce the frequency of bleeding by up to …
[HTML][HTML] Randomized, prospective clinical trial of recombinant factor VIIa for secondary prophylaxis in hemophilia patients with inhibitors
BA Konkle, LS Ebbesen, E Erhardtsen… - Journal of Thrombosis …, 2007 - Elsevier
Background: Hemophilic patients with factor VIII (FVIII) and FIX inhibitors suffer from frequent
bleeding episodes and reduced quality of life. Objectives: To evaluate whether secondary …
bleeding episodes and reduced quality of life. Objectives: To evaluate whether secondary …
Early long‐term FEIBA prophylaxis in haemophilia A patients with inhibitor after failing immune tolerance induction: a prospective clinical case series
CE Ettingshausen, W Kreuz - Haemophilia, 2010 - Wiley Online Library
Persistent high‐titre inhibitors after immune tolerance induction (ITI) increase the risks of
haemorrhage and arthropathy, resulting in high morbidity and mortality. Long‐term …
haemorrhage and arthropathy, resulting in high morbidity and mortality. Long‐term …
Randomized comparison of prophylaxis and on‐demand regimens with FEIBA NF in the treatment of haemophilia A and B with inhibitors
SV Antunes, S Tangada, O Stasyshyn… - …, 2014 - Wiley Online Library
Factor replacement therapy for the treatment of moderate to severe haemophilia A and B
can be complicated by the production of inhibitory alloantibodies to factor VIII (FVIII) or factor …
can be complicated by the production of inhibitory alloantibodies to factor VIII (FVIII) or factor …
PRO-PACT: retrospective observational study on the prophylactic use of recombinant factor VIIa in hemophilia patients with inhibitors
G Young, G Auerswald, V Jimenez-Yuste, T Lambert… - Thrombosis research, 2012 - Elsevier
INTRODUCTION: Hemophilia patients with inhibitors have frequent bleeding episodes and
often develop hemophilic arthropathy which is in contradistinction to non-inhibitor patients …
often develop hemophilic arthropathy which is in contradistinction to non-inhibitor patients …
FEIBA prophylaxis for patients with haemophilia and inhibitors
LA Valentino - Haemophilia, 2006 - Wiley Online Library
Prophylaxis with clotting factor concentrates has been shown to prevent bleeding episodes
and improve quality of life in patients with severe haemophilia A or B. The benefits of long …
and improve quality of life in patients with severe haemophilia A or B. The benefits of long …
Prophylaxis in haemophilia with inhibitors: update from international experience
M Carcao, T Lambert - Haemophilia, 2010 - Wiley Online Library
An antibody response to therapeutically administered factor VIII (FVIII) can occur in up to
30% of patients with haemophilia, resulting in the production of inhibitors that neutralize FVIII …
30% of patients with haemophilia, resulting in the production of inhibitors that neutralize FVIII …
[HTML][HTML] A randomized comparison of two prophylaxis regimens and a paired comparison of on‐demand and prophylaxis treatments in hemophilia A management
LA Valentino, V Mamonov, A Hellmann… - Journal of thrombosis …, 2012 - Elsevier
Background: Prophylaxis with factor (F) VIII is considered the optimal treatment for managing
hemophilia A patients without inhibitors. Objectives: To compare the efficacy of two …
hemophilia A patients without inhibitors. Objectives: To compare the efficacy of two …
Spanish Consensus Guidelines on prophylaxis with bypassing agents in patients with haemophilia and inhibitors
MF López-Fernández, CA Roca… - Thrombosis and …, 2016 - thieme-connect.com
Prophylaxis with the blood clotting factor, factor VIII (FVIII) is ineffective for individuals with
haemophilia A and high-titre inhibitors to FVIII. Prophylaxis with the FVIII bypassing agents …
haemophilia A and high-titre inhibitors to FVIII. Prophylaxis with the FVIII bypassing agents …
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