Peptide agonists and antagonists with potential application in neurological disorders
A Russo, SL Manna, G Morelli… - Recent Patents on …, 2015 - ingentaconnect.com
Background: Peptides are usually used to investigate regulatory networks and protein
function. They can also be used in therapeutic research: They are employed both to identify …
function. They can also be used in therapeutic research: They are employed both to identify …
Editorial (Thematic Issue: Peptides as a Novel Therapeutic Approach for Neurodegenerative Diseases)
Z Khan - Current Medicinal Chemistry, 2014 - ingentaconnect.com
Peptides and proteins are the natural means of activating and inhibiting cellular
mechanisms. Normal functions of the central nervous system (CNS) largely dependent on …
mechanisms. Normal functions of the central nervous system (CNS) largely dependent on …
Peptides: important tools for the treatment of central nervous system disorders
L Malavolta, FR Cabral - Neuropeptides, 2011 - Elsevier
This review shows some classical applications of peptides and suggests there is great
promise for the treatment of various central nervous system diseases. Actually, peptides are …
promise for the treatment of various central nervous system diseases. Actually, peptides are …
Peptide based therapy for neurological disorders
Peptides are small molecules composed of amino acids linked together by peptide bonds.
The targeted action of these peptides along with their magnificent ability to reach locations in …
The targeted action of these peptides along with their magnificent ability to reach locations in …
Whether short peptides are good candidates for future neuroprotective therapeutics?
R Perlikowska - Peptides, 2021 - Elsevier
Neurodegenerative diseases are a broad group of largely debilitating, and ultimately
terminal conditions resulting in progressive degeneration of different brain regions. The …
terminal conditions resulting in progressive degeneration of different brain regions. The …
Peptide Drugs: Current Status and it's Applications in the Treatment of Various Diseases
C Chandarana, I Juwarwala, S Shetty… - Current Drug Research …, 2024 - ingentaconnect.com
Peptides represent a class of natural molecules with diverse physiological functions,
including hormone regulation, neurotransmission, and immune modulation. In recent years …
including hormone regulation, neurotransmission, and immune modulation. In recent years …
Potentials of neuropeptides as therapeutic agents for neurological diseases
Despite recent leaps in modern medicine, progress in the treatment of neurological diseases
remains slow. The near impermeable blood-brain barrier (BBB) that prevents the entry of …
remains slow. The near impermeable blood-brain barrier (BBB) that prevents the entry of …
Concepts for biologically active peptides
AJ Kastin, W Pan - Current pharmaceutical design, 2010 - ingentaconnect.com
Here we review a unique aspect of CNS research on biologically active peptides that started
against a background of prevalent dogmas but ended by exerting considerable influence on …
against a background of prevalent dogmas but ended by exerting considerable influence on …
Peptides as receptor ligand drugs and their relationship to G-coupled signal transduction
GJ Mizejewski - Expert Opinion on Investigational Drugs, 2001 - Taylor & Francis
Peptides act as effector agents that regulate and/or mediate physiological processes,
serving as hormones, neurotransmitters and signal transducing factors. The low molecular …
serving as hormones, neurotransmitters and signal transducing factors. The low molecular …
Peptide therapeutics for CNS indications
P McGonigle - Biochemical Pharmacology, 2012 - Elsevier
Neuropeptides play a crucial role in the normal function of the central nervous system and
peptide receptors hold great promise as therapeutic targets for the treatment of several CNS …
peptide receptors hold great promise as therapeutic targets for the treatment of several CNS …