In this study, we compared the failure rates of fosfomycin and nitrofurantoin for
uncomplicated urinary tract infections. We used Meuhedet Health Services' large database …

This multicenter clinical trial compared single-dose fosfomycin tromethamine with a 7-day
course of nitrofurantoin for the treatment of acute uncomplicated lower urinary tract infection …

Importance The use of nitrofurantoin and fosfomycin has increased since guidelines began
recommending them as first-line therapy for lower urinary tract infection (UTI). Objective To …

Urinary tract infections (UTI) are among the most frequent medical conditions requiring
outpatient treatment. Single dose oral fosfomycin (300 mg) and the older nitrofurantoin (100 …

Background Uncomplicated urinary tract infections (UTIs) are common among female
patients. According to the national guidelines of the Dutch College of General Practitioners …

Methods The aim was to assess the comparative clinical efficacy of a 5-day treatment with
nitrofurantoin (100 mg three times a day) and single dose of fosfomycin-trometamol (3 g …

Fosfomycin, approved in the United States only for cystitis, is an attractive alternative for oral
treatment of outpatient complicated urinary tract infections (cUTIs) as it has antimicrobial …

A multinational, open-label, analyst-blinded, randomized clinical trial has shown that 5-day
nitrofurantoin is more likely to result in clinical and microbiological resolution of acute …

Fosfomycin is recommended as one of the first-line agents for treatment of urinary tract
infections (UTIs) in the latest guidelines endorsed by the Infectious Diseases Society of …

Background. Oral therapeutic options for the treatment of urinary tract infections (UTIs) have
become limited due to the emergence of Gram-negative bacteria resistant to …