SUN-domain and KASH-domain proteins during development, meiosis and disease
A Fridkin, A Penkner, V Jantsch… - Cellular and molecular life …, 2009 - Springer
SUN-domain proteins interact directly with KASH-domain proteins to form protein complexes
that connect the nucleus to every major cytoskeleton network. SUN-KASH protein …
that connect the nucleus to every major cytoskeleton network. SUN-KASH protein …
[HTML][HTML] Conserved SUN-KASH interfaces mediate LINC complex-dependent nuclear movement and positioning
Many nuclear positioning events involve linker of nucleoskeleton and cytoskeleton (LINC)
complexes, which transmit forces generated by the cytoskeleton across the nuclear …
complexes, which transmit forces generated by the cytoskeleton across the nuclear …
Building and breaking mechanical bridges between the nucleus and cytoskeleton: Regulation of LINC complex assembly and disassembly
The nucleus is physically coupled to the cytoskeleton through LINC complexes,
macromolecular bridges composed of SUN and KASH proteins that span the nuclear …
macromolecular bridges composed of SUN and KASH proteins that span the nuclear …
UNC-83 IS a KASH protein required for nuclear migration and is recruited to the outer nuclear membrane by a physical interaction with the SUN protein UNC-84
MD McGee, R Rillo, AS Anderson… - Molecular biology of the …, 2006 - Am Soc Cell Biol
UNC-84 is required to localize UNC-83 to the nuclear envelope where it functions during
nuclear migration. A KASH domain in UNC-83 was identified. KASH domains are conserved …
nuclear migration. A KASH domain in UNC-83 was identified. KASH domains are conserved …
Molecular models of LINC complex assembly at the nuclear envelope
Large protein complexes assemble at the nuclear envelope to transmit mechanical signals
between the cytoskeleton and nucleoskeleton. These protein complexes are known as the …
between the cytoskeleton and nucleoskeleton. These protein complexes are known as the …
[HTML][HTML] KASH and SUN proteins
DA Starr - Current Biology, 2011 - cell.com
What are KASH proteins? KASH proteins (Klarsicht, ANC-1, Syne homology) are C-tail-
anchored membrane proteins, which are targeted specifically to the outer membrane of the …
anchored membrane proteins, which are targeted specifically to the outer membrane of the …
LINCing complex functions at the nuclear envelope: what the molecular architecture of the LINC complex can reveal about its function
A Rothballer, TU Schwartz, U Kutay - Nucleus, 2013 - Taylor & Francis
Linker of nucleoskeleton and cytoskeleton (LINC) complexes span the double membrane of
the nuclear envelope (NE) and physically connect nuclear structures to cytoskeletal …
the nuclear envelope (NE) and physically connect nuclear structures to cytoskeletal …
Accessorizing and anchoring the LINC complex for multifunctionality
W Chang, HJ Worman, GG Gundersen - Journal of Cell Biology, 2015 - rupress.org
The linker of nucleoskeleton and cytoskeleton (LINC) complex, composed of outer and inner
nuclear membrane Klarsicht, ANC-1, and Syne homology (KASH) and Sad1 and UNC-84 …
nuclear membrane Klarsicht, ANC-1, and Syne homology (KASH) and Sad1 and UNC-84 …
LINC complex proteins in development and disease
HF Horn - Current topics in developmental biology, 2014 - Elsevier
The LINC complex spans the nuclear envelope and plays critical roles in coordinating
nuclear and cytoplasmic activities and in organizing nuclear and cytoskeletal features. LINC …
nuclear and cytoplasmic activities and in organizing nuclear and cytoskeletal features. LINC …
KASH'n Karry: The KASH domain family of cargo‐specific cytoskeletal adaptor proteins
DA Starr, JA Fischer - Bioessays, 2005 - Wiley Online Library
A diverse family of proteins has been discovered with a small C‐terminal KASH domain in
common. KASH domain proteins are localized uniquely to the outer nuclear envelope …
common. KASH domain proteins are localized uniquely to the outer nuclear envelope …