Bone metastases from carcinomas are epidemiologically rising because of the increased
survival rate of oncologic patients, related to several factors such as improvement of primary …

Bone metastases are common complications of many cancers. Among the mechanisms that
set the scene for the development of bone metastases, several are shared by all forms of …

The skeleton is the most common organ to be affected by metastatic cancer, and tumors
arising from the breast, prostate, thyroid, lung, and kidney possess a special propensity to …

Publisher Summary The bone is the most common site of metastases for tumors from breast,
prostate, lung, kidney and thyroid. An accurate diagnosis is dependent upon the …

Bone metastases of solid tumors not only cause significant morbility in cancer patients, but
also usually indicate that the cancer has progressed into a non-curable stage. Recent …

Metastasis to the bone represents a frequent complication of visceral cancers, most
commonly in patients with advanced breast, prostate, and lung cancer. More than 50% of …

CLINICALLY SIGNIFICANT TUMORS with bone metastasis are seen with diminishing
frequency. Surgery with adjuvant chemotherapy and other treatment modalities are often …

Although primary bone tumors are rare, metastatic tumors involving bone are common, and
their incidence increase with age. As many as 60 percent of cancer patients will be found to …

Alterations in bone architecture and mineral metabolism are common complications of
malignancy. Cancers such as breast, prostate, and lung can affect the skeleton either …

Bone metastases are a late event in tumor progression, contributing to morbidity and
mortality and decreasing patient quality of life. Cancer colonization of the skeleton is …