Yohimbine is an alpha‐2 adrenoceptor antagonist that has been used in numerous studies
as a pharmacological stressor in rodents, monkeys and humans. Recently, yohimbine has …

Abstract Rationale and Objectives Relapse to alcohol use during abstinence or maladaptive
eating habits during dieting is often provoked by stress. The anxiogenic drug yohimbine …

Acute exposure to the pharmacological stressor yohimbine induces relapse to both food and
drug seeking in a rat model. However, no systematic studies on the effects of chronic stress …

Converging evidence suggests a role for noradrenergic mechanisms in stress-induced
reinstatement of cocaine seeking in animals. Yohimbine, an α 2-adrenoceptor antagonist, is …

BACKGROUND: Brain noradrenaline is involved in footshock stress-induced reinstatement
of drug seeking in a rat relapse model. We studied whether yohimbine, an α-2 adrenoceptor …

Rationale In laboratory animals, the biological stressor yohimbine (α 2-noradrenergic
autoreceptor antagonist) promotes drug seeking. Human laboratory studies have …

Although exposure to acute stress has been shown to reinstate extinguished responding for
a wide variety of drugs, no studies have investigated stress-induced reinstatement in …

Rationale Developing models to efficiently explore the mechanisms by which stress can
mediate reinstatement of drug-seeking behavior is crucial to the development of new …

The major problem in treating excessive eating is high rates of relapse to maladaptive eating
habits during diet treatments; this relapse is often induced by stress or anxiety states …

Rationale and objectives Yohimbine is an alpha-2 adrenoreceptor antagonist that provokes
stress-and anxiety-like responses in both humans and laboratory animals. In rats, yohimbine …