Visceral adipose tissue (VAT)—fat stored around the internal organs—has been suggested
as an independent risk factor for cardiovascular and metabolic disease,–, as well as all …

Obesity is a chronic condition associated with increased morbidity and mortality and is a risk
factor for a number of other diseases including type 2 diabetes and cardiovascular disease …

To identify genetic loci influencing central obesity and fat distribution, we performed a meta-
analysis of 16 genome-wide association studies (GWAS, N= 38,580) informative for adult …

Genome-wide association studies (GWASs) have identified thousands of genetic loci
associated with cardiometabolic traits including type 2 diabetes (T2D), lipid levels, body fat …

Body fat distribution, particularly centralized obesity, is associated with metabolic risk above
and beyond total adiposity. We performed genome-wide association of abdominal adipose …

Obesity is heritable and predisposes to many diseases. To understand the genetic basis of
obesity better, here we conduct a genome-wide association study and Metabochip meta …

Common human diseases result from the interplay of many genes and environmental
factors. Therefore, a more integrative biology approach is needed to unravel the complexity …

Subcutaneous adipose tissue stores excess lipids and maintains energy balance. We
performed expression quantitative trait locus (eQTL) analyses by using abdominal …

Obesity increases the risks of developing cardiovascular and metabolic diseases and
degrades quality of life, ultimately increasing the risk of death. However, not all forms of …

Sex differences in adipose tissue distribution and function are associated with sex
differences in cardiometabolic disease. While many studies have revealed sex differences in …