Distinct acetylation of Trypanosoma cruzi histone H4 during cell cycle, parasite differentiation, and after DNA damage
Histones of trypanosomes are quite divergent when compared to histones of most
eukaryotes. Nevertheless, the histone H4 of Trypanosoma cruzi, the protozoan that causes …
eukaryotes. Nevertheless, the histone H4 of Trypanosoma cruzi, the protozoan that causes …
[HTML][HTML] Expression of non-acetylatable lysines 10 and 14 of histone H4 impairs transcription and replication in Trypanosoma cruzi
TCP Ramos, VS Nunes, SC Nardelli… - Molecular and …, 2015 - Elsevier
The histone H4 from Trypanosomatids diverged from other eukaryotes in the N-terminus, a
region that undergoes post-translation modifications involved in the control of gene …
region that undergoes post-translation modifications involved in the control of gene …
Post-translational modifications of Trypanosoma cruzi histone H4
JPC da Cunha, ES Nakayasu, IC de Almeida… - Molecular and …, 2006 - Elsevier
Histone tails provide sites for a variety of post-translational modifications implicated in the
control of gene expression and chromatin assembly. As both histones and control of gene …
control of gene expression and chromatin assembly. As both histones and control of gene …
Histone H1 of Trypanosoma cruzi Is Concentrated in the Nucleolus Region and Disperses upon Phosphorylation during Progression to Mitosis
LM Gutiyama, JPC da Cunha, S Schenkman - Eukaryotic cell, 2008 - Am Soc Microbiol
Phosphorylation of histone H1 is intimately related to the cell cycle progression in higher
eukaryotes, reaching maximum levels during mitosis. We have previously shown that in the …
eukaryotes, reaching maximum levels during mitosis. We have previously shown that in the …
Histone H1 is phosphorylated in non-replicating and infective forms of Trypanosoma cruzi
The nuclear structure changes during the differentiation from growing to infective stages of
Trypanosoma cruzi. As histone modifications have been correlated with structural and …
Trypanosoma cruzi. As histone modifications have been correlated with structural and …
Chromatin Proteomics Reveals Variable Histone Modifications during the Life Cycle of Trypanosoma cruzi
TCL de Jesus, VS Nunes, MC Lopes… - Journal of proteome …, 2016 - ACS Publications
Histones are well-conserved proteins that form the basic structure of chromatin in eukaryotes
and undergo several post-translational modifications, which are important for the control of …
and undergo several post-translational modifications, which are important for the control of …
Acetylation of histone H4K4 is cell cycle regulated and mediated by HAT3 in Trypanosoma brucei
TN Siegel, T Kawahara, JA DeGrasse… - Molecular …, 2008 - Wiley Online Library
Post‐translational histone modifications have been studied intensively in several
eukaryotes. It has been proposed that these modifications constitute a 'histone code'that …
eukaryotes. It has been proposed that these modifications constitute a 'histone code'that …
Trypanosoma cruzi histone H1 is phosphorylated in a typical cyclin dependent kinase site accordingly to the cell cycle
Histone H1 of most eukaryotes is phosphorylated during the cell cycle progression and
seems to play a role in the regulation of chromatin structure, affecting replication and …
seems to play a role in the regulation of chromatin structure, affecting replication and …
H 1 histone and histone variants in Trypanosoma cruzi
GC Toro, N Galanti - Experimental cell research, 1988 - Elsevier
Trypanosoma cruzi chromatin is not condensed in chromosomes during mitosis. In previous
studies a characteristic H 1 was not found in SDS or in acid-urea-PAGE. Consequently, it …
studies a characteristic H 1 was not found in SDS or in acid-urea-PAGE. Consequently, it …
Histone modifications in Trypanosoma brucei
V Mandava, JP Fernandez, H Deng, CJ Janzen… - Molecular and …, 2007 - Elsevier
Several biological processes in Trypanosoma brucei are affected by chromatin structure,
including gene expression, cell cycle regulation, and life-cycle stage differentiation. In …
including gene expression, cell cycle regulation, and life-cycle stage differentiation. In …